In:
Journal of Child Psychology and Psychiatry, Wiley, Vol. 55, No. 12 ( 2014-12), p. 1372-1379
Abstract:
This study's primary aim was to examine age‐specific associations between GABRA 2 , rule breaking, problematic alcohol use, and substance abuse symptomatology. The secondary aim was to examine the extent to which rule breaking mediates the GABRA 2‐ substance abuse relationship. Methods A sample ( n = 518) of primarily male (70.9%) and White (88.8%) adolescents from the Michigan Longitudinal Study was assessed from ages 11–18. Age‐specific effects of GABRA 2 on rule breaking, problematic alcohol use, and substance abuse symptomatology were examined using nested path models. The role of rule breaking as a mediator in the association between GABRA 2 and substance abuse outcomes was tested using prospective cross‐lagged path models. Results GABRA 2 is significantly ( p 〈 0.05) associated with rule breaking in mid‐ to late‐adolescence, but not substance abuse symptomatology across adolescence. GABRA 2 effects on problematic alcohol use and substance abuse symptomatology operate largely (45.3% and 71.1%, respectively, p 〈 0.05) via rule breaking in midadolescence. Conclusions GABRA 2 represents an early risk factor for an externalizing pathway to the development of problematic alcohol and drug use.
Type of Medium:
Online Resource
ISSN:
0021-9630
,
1469-7610
DOI:
10.1111/jcpp.2014.55.issue-12
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
1470297-6
SSG:
5,2
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