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  • 1
    In: Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 139, No. 4_Supplement ( 2016-04-01), p. 2026-2026
    Abstract: The goal of timely and accurate acoustics modeling in the ocean depends on accurate environmental input information. Acoustic propagation modeling has improved to the point of possibly being ahead of ocean dynamical modeling from the standpoint that some significant ocean features having strong acoustic effects are not faithfully reproduced in many models, particularly data-driven ocean models. This in part stems from the fact that ocean models have developed with other goals in mind, but computational limitations also play a role. The Integrated Ocean Dynamics and Acoustics (IODA) MURI project has as its goals improving ocean models, and also making continued improvements to acoustic models, for the purpose of advancing ocean acoustic modeling and prediction capabilities. Two major focuses are improved internal tide forecasting and improved nonlinear internal wave forecasting, which require pushing the state of the art in data-constrained mesoscale feature modeling as well as developing specialized high-resolution tools. Results are reported on efforts to evaluate internal-tide accuracy in data-constrained models, to insert typically unresolved nonlinear internal waves with nonhydrostatic pressure dynamics into these models, and to make acoustical condition forecasts within three-dimensional operational volumes filled with internal waves.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2016
    detail.hit.zdb_id: 1461063-2
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  • 2
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 1998
    In:  The Journal of the Acoustical Society of America Vol. 103, No. 5_Supplement ( 1998-05-01), p. 2960-2961
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 103, No. 5_Supplement ( 1998-05-01), p. 2960-2961
    Abstract: The gas bubbles in liquid are the strong scatters of the sound propagation in such liquid. A liquid containing microbubbles is used as an effective ultrasound contrast agent in medical diagnosis to improve the contrast of the ultrasonic image. However, the existence of bubbles in liquid may enhance its nonlinearity parameter. In our previous paper, the preliminary results of some ultrasound contrast agents were reported and their large values of the nonlinearity parameter were obtained. This paper is devoted to an experimental demonstration of the influence of microbubbles on the nonlinearity parameter B/A values. These include measuring the dependence of B/A values of Echovist 300 on time. Results show that B/A values decrease with time (from 2678 to 16 over 45 min). B/A values of human blood with a different portion of Echovist were also studied. Larger B/A values are obtained with more Echovist. B/A values of a kind aqua, such as 76% Injectio Meglumini Diatrizoatis Composita (MDC), were studied before and after sonication with different bubble contents. Results indicate that the values of nonlinearity parameter depend on the presence of microbubbles obviously. Some explanation of this effect is discussed. [Work supported by NSF of China.]  
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 1998
    detail.hit.zdb_id: 1461063-2
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  • 3
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 2020
    In:  The Journal of the Acoustical Society of America Vol. 148, No. 4 ( 2020-10-01), p. EL375-EL381
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 148, No. 4 ( 2020-10-01), p. EL375-EL381
    Abstract: Acoustic droplet vaporization (ADV) is an important process that enables the theragnostic application of acoustically activated droplets, where the nucleation of inertial cavitation (IC) activity must be precisely controlled. This Letter describes threshold pressure measurements for ADV and acoustic emissions consistent with IC activity of lipid-shelled non-superheated perfluoropentane nanodroplets over a range of physiologically relevant concentrations at 1.1-MHz. Under the frequency investigated, results show that the thresholds were relatively independent of concentration for intermediate concentrations (105, 106, and 107 droplets/ml), thus indicating an optimal range of droplet concentrations for conducting threshold studies. For the highest concentration, the difference between the threshold for IC and the threshold for ADV was greatly reduced, suggesting that it might prove difficult to induce ADV without concomitant IC in applications that employ higher concentrations.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2020
    detail.hit.zdb_id: 1461063-2
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  • 4
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 1991
    In:  The Journal of the Acoustical Society of America Vol. 90, No. 4_Supplement ( 1991-10-01), p. 2341-2342
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 90, No. 4_Supplement ( 1991-10-01), p. 2341-2342
    Abstract: A broad enhancement of the form function for these shells is known to be present in the mid-frequency range. A ray model of the form function in this region was previously demonstrated for cylinders and spheres [N. H. Sun and P. L. Marston, J. Acoust. Soc. Am. 89, 1949 (1991)] and the enhancement was found to be associated with contributions to the scattering from the subsonic surface guided wave frequently designated as A & lt;lu & gt;0 & lt;bu & gt;− & lt;lux & gt;. The consequences of this enhancement were investigated for spherical shells by synthesizing the response to tone bursts from an evaluation of the exact partial wave series over the sampled spectrum of the burst [L. Zhang, M. S. dissertation, Washington State University, 1991]. This was compared with a ray approximation for the earliest contribution for this wave, which circumnavigates only the backside of the shell. The amplitude from the ray model is ‖f0,l‖ ≊ 8πβl(c/cl)exp(−πβl), where the surface wave parameters cl and βl are found from the exact elastic equation for the roots of Dν(ka)=0. Both the Fourier synthesis and ray models show a broad enhancement which for a 2.5% stainless steel shell peaks at ka≊46 where ‖f0,l‖ ≊ 3.1 and the exact results differ by only 3%. Neglecting dispersion the peak occurs where βl=π−1. [Work supported by ONR.]
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 1991
    detail.hit.zdb_id: 1461063-2
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  • 5
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 2014
    In:  The Journal of the Acoustical Society of America Vol. 135, No. 1 ( 2014-01-01), p. 537-544
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 135, No. 1 ( 2014-01-01), p. 537-544
    Abstract: One application of acoustic droplet vaporization (ADV), a method of converting biocompatible microdroplets into microbubbles, is to enhance locally high intensity focused ultrasound (HIFU) therapy. Two objectives are pursued here: (1) the controlled creation of a bubble trench prior to HIFU using ADV and (2) use of the trench for increasing ablation volumes, lowering acoustic powers, and decreasing therapy duration. Thermally responsive phantoms were made with perfluorocarbon emulsion. Compound lesions were formed in a laboratory setting and a clinical magnetic resonance imaging (MRI)-guided HIFU system. Linear and spiral patterned compound lesions were generated in trenches. A larger fraction of the HIFU beam is contained to increase the generation of heat. Using the laboratory system, a 90 mm linear length spiral trench was formed in 30 s with mechanical beam steering. Comparatively, the clinical HIFU system formed a 19.9 mm linear length spiral trench in approximately 1 s with electronic beam steering. Lesions were imaged optically and with MRI. A uniform thermal ablation volume of 3.25 mL was achieved in 55.4 s (4-times faster than standard clinical HIFU and 14-times larger volume versus sum of individual lesions). Single lesions showed a 400% volume increase.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2014
    detail.hit.zdb_id: 1461063-2
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  • 6
    Online Resource
    Online Resource
    Elsevier BV ; 2022
    In:  Journal of Memory and Language Vol. 125 ( 2022-08), p. 104333-
    In: Journal of Memory and Language, Elsevier BV, Vol. 125 ( 2022-08), p. 104333-
    Type of Medium: Online Resource
    ISSN: 0749-596X
    RVK:
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 1469677-0
    SSG: 5,2
    SSG: 7,11
    SSG: 5,3
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  • 7
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 2012
    In:  The Journal of the Acoustical Society of America Vol. 132, No. 3_Supplement ( 2012-09-01), p. 1907-1907
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 132, No. 3_Supplement ( 2012-09-01), p. 1907-1907
    Abstract: Recent theoretical advances concerning the geometrical interpretation of acoustic radiation forces [L. K. Zhang and P. L. Marston, Phys. Rev. E 84, 035601R (2011); L. K. Zhang and P. L. Marston, J. Acoust. Soc. Am. 131, EL329-EL335 (2012)] and the scaling of acoustic radiation torques for symmetric objects in beams and in standing waves with increasing helicity [L. K. Zhang and P. L. Marston, Phys. Rev. E 84, 065601R (2011)] will be summarized. For spheres in beams it has been possible to find situations giving transversely stable radiation forces using finite elements. The predicted scaling properties of acoustic torques have been verified in an investigation by an independent group [C. E. M. Demore et al., Phys. Rev. Lett. 108, 194301 (2012); A. G. Smart, Physics Today 65 (6), 18-20 (2012)]. This work will be examined in the context of broader discussions with, and/or a few of the interests of, Wes Nyborg and his practical analysis of acoustic streaming [W. L. Nyborg, in Nonlinear Acoustics, edited by M. F. Hamilton and D. T. Blackstock (Academic Press, San Diego, CA, 1998)] pp. 207-231. [Marston and Thiessen were supported in part by ONR. Zhang was supported in part by NASA.]
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2012
    detail.hit.zdb_id: 1461063-2
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  • 8
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 2010
    In:  The Journal of the Acoustical Society of America Vol. 127, No. 3_Supplement ( 2010-03-01), p. 1975-1975
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 127, No. 3_Supplement ( 2010-03-01), p. 1975-1975
    Abstract: Micron- and nano-sized colloids are being studied in diagnostic and therapeutic applications of ultrasound (US). Unlike clinically utilized microbubbles, emulsions possess unique physiochemical properties that could translate into distinct, clinical benefits beyond conventional contrast agents. Droplets, composed of a superheated liquid, can be phase transitioned into bubbles using US, a process known as acoustic droplet vaporization (ADV). Droplets, transpulmonary in size, transition into bubbles upon ADV and can reach diameters that occlude capillaries and arrest blood flow in the vascular bed. Examples of ADV in diagnostic and therapeutic applications will be presented. First, ADV has been used in phase aberration correction in transcranial US imaging. Second, ADV-generated microbubbles can reduce and occlude renal perfusion in vivo. Third, the effects of thermal therapy using high-intensity focused ultrasound (HIFU) has been enhanced and controlled more effectively using ADV. Fourth, ADV has been utilized as a release mechanism for therapeutic agents that are incorporated into the emulsion. In all applications, the physiochemical properties of the droplets coupled with the spatial and temporal control afforded by ADV-generated microbubbles are crucial to the success of each ADV development. [This work was supported in part by NIH Grant 5R01EB000281.]
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2010
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  • 9
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 1991
    In:  The Journal of the Acoustical Society of America Vol. 90, No. 4_Supplement ( 1991-10-01), p. 2341-2341
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 90, No. 4_Supplement ( 1991-10-01), p. 2341-2341
    Abstract: For certain elastic plates in a vacuum, the group velocity near the mode threshold of a Lamb wave becomes negative and the average power flow is directed opposite the phase velocity. This is known as a backward wave. It is proposed that backward leaky Lamb waves on thin fluid loaded shells contribute to the high-frequency enhancement that has been noted recently by several researchers. Though the ka of that enhancement lies close to that of the longitudinal or thickness resonance, ray models of the internal reverberations do not adequately describe the structure in the form function where the group velocity of the s1 wave can be negative [S. G. Kargl and P. L. Marston, J. Acoust. Soc. Am. 89, 2545–2558 (1991)]. In the backward-ray model a leaky wave with a phase velocity in the clockwise direction propagates energy in the counterclockwise direction. As a result, energy is leaked off toward the source without having circumnavigated the backside of the shell, having propagated an angle of only 2θl on the shell where sin θl=c/cl. The contribution to the backscattering has the approximate magnitude ‖f0,l‖ ≊‖ Gl‖exp (−2θlβl) and only occurs where the radiation damping βl is large. Some discrepancies in previous ray models for thick and thin shells are partially accounted for and a prompt surface ray mechanism for tone burst scattering is evident. [Work supported by ONR.]
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 1991
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  • 10
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 2011
    In:  The Journal of the Acoustical Society of America Vol. 130, No. 4_Supplement ( 2011-10-01), p. 2403-2403
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 130, No. 4_Supplement ( 2011-10-01), p. 2403-2403
    Abstract: The resolution of acoustic imaging system is restricted by diffraction limit. To beat this limit, early research shows acoustic metamaterials that can manipulate acoustic waves artificially and may act as lens to achieve subwavelength resolution. However, these solutions suffer significant loss therefore lack convincing experimental demonstration. Recent study suggested that arrays of metallic nanorods or nanowire can be used as lens for optical imaging at subwavelength resolution. Similar acoustic hyperlens designs have also been explored, and latest experimental result provided resolution of wavelength/7. Here presented is a holey structured endoscope which supports the transmission of the otherwise-evanescent waves over distances, therefore beating diffraction limit and achieving deep subwavelength imaging. Experimental demonstration shows clear image with feature size of wavelength/50. Such a metamaterial endoscope brings new perspectives to the applications of medical ultrasonography, sonar and ultrasonic non-destructive evaluation.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2011
    detail.hit.zdb_id: 1461063-2
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