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  • Comparative Studies. Non-European Languages/Literatures  (3)
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  • Comparative Studies. Non-European Languages/Literatures  (3)
RVK
  • 1
    Online Resource
    Online Resource
    A new composite particle for both contrast-enhanced ultrasound imaging and cell therapy
    Acoustical Society of America (ASA) ; 2012
    In:  The Journal of the Acoustical Society of America Vol. 131, No. 4_Supplement ( 2012-04-01), p. 3323-3323
    Details
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 131, No. 4_Supplement ( 2012-04-01), p. 3323-3323
    Abstract: In this paper, a new composite nano-particle for both contrast-enhanced ultrasound imaging and cell therapy is introduced. The carbon nanotubes are used for carriers due to their unique hollow structure, nano-diameter and good biocompatibility. The targeted protein, the hematoporphyrin and the gold nanoparticles are assembled on the surface of the carbon nanotubes. The targeted protein is used as tumor localization. As a kind of sonosensitizer, the hematoporphyrin can produce the singlet oxygen while being activated by ultrasound and are studied for its effects of antitumor and apoptosis induction recently. It is worthwhile to note that the singlet oxygen has a very short lifetime and will transfer to triplet oxygen with light emission band at 1268 nm, or 634 nm and 703 nm. Triplet oxygen is the ground state of the oxygen molecule and much of them will form nano oxygen bubbles under body temperature which can be used as contrast-enhanced ultrasound imaging agent. At the same time, the gold nanoparticles which have good biocompatibility can absorb the light emission and produce the acoustic signals of some bandwidth. This work is supported by the National Natural Science Foundation of China (No. 10804085, 11174223 and 50603019), and the Shanghai Nano Special Foundation(No. 1052nm05400)
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    URL: Article
    DOI: 10.1121/1.4708436
    RVK:
    EQ 1000
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2012
    detail.hit.zdb_id: 1461063-2
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Relative contributions of temporal and spectral cues for Mandarin and Cantonese tone recognition
    Acoustical Society of America (ASA) ; 2012
    In:  The Journal of the Acoustical Society of America Vol. 131, No. 4_Supplement ( 2012-04-01), p. 3478-3478
    Details
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 131, No. 4_Supplement ( 2012-04-01), p. 3478-3478
    Abstract: Despite good speech perception performance in quiet, pitch perception remains a challenge for cochlear-implant users. The current vocoder-based processing technique in cochlear implants preserves temporal envelope and coarse spectral information. This information, however, is insufficient to support high-level performance for tone perception in tonal languages (e.g., Mandarin and Cantonese), particularly in noise. Mandarin has four lexical tones and Cantonese has six lexical tones. Each lexical tone has different fundamental frequency contours. The temporal envelope of the signal also differs among different tones. In this talk, we will first discuss the relative contributions of temporal and spectral envelope and fine structure cues for Mandarin and Cantonese tone perception. We will then describe a new signal processing algorithm developed at the Chinese University of Hong Kong that aims to enhance temporal periodicity cues for Cantonese tone perception in noise. We will present findings from normal-hearing and cochlear-implant listeners, which demonstrate a significant improvement of Cantonese tone perception in noise with this new algorithm.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    URL: Article
    DOI: 10.1121/1.4709124
    RVK:
    EQ 1000
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2012
    detail.hit.zdb_id: 1461063-2
    Location Call Number Limitation Availability
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Cantonese tone recognition with enhanced temporal periodicity cues
    Acoustical Society of America (ASA) ; 2009
    In:  The Journal of the Acoustical Society of America Vol. 126, No. 1 ( 2009-07-01), p. 327-337
    Details
    In: The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 126, No. 1 ( 2009-07-01), p. 327-337
    Abstract: This study investigated the contributions of temporal periodicity cues and the effectiveness of enhancing these cues for Cantonese tone recognition in noise. A multichannel noise-excited vocoder was used to simulate speech processing in cochlear implants. Ten normal-hearing listeners were tested. Temporal envelope and periodicity cues (TEPCs) below 500Hz were extracted from four frequency bands: 60–500, 500–1000, 1000–2000, and 2000–4000Hz. The test stimuli were obtained by combining TEPC-modulated noise signals from individual bands. For periodicity enhancement, temporal fluctuations in the range 20–500Hz were replaced by a sinusoid with frequency equal to the fundamental frequency of original speech. Tone identification experiments were carried out using disyllabic word carriers. Results showed that TEPCs from the two high-frequency bands were more important for tone identification than TEPCs from the low-frequency bands. The use of periodicity-enhanced TEPCs led to consistent improvement of tone identification accuracy. The improvement was more significant at low signal-to-noise ratios, and more noticeable for female than for male voices. Analysis of error distributions showed that the enhancement method reduced tone identification errors and did not show any negative effect on the recognition of segmental structures.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    URL: Article
    DOI: 10.1121/1.3117447
    RVK:
    EQ 1000
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2009
    detail.hit.zdb_id: 1461063-2
    Location Call Number Limitation Availability
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    Online Resource
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