In:
The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 83, No. S1 ( 1988-05-01), p. S22-S22
Abstract:
In order to clarify the combined effects of whole-body vibration and noise on dopamine (DA) metabolism within the brain, which is known to regulate the response of the organism to various stimuli, the DA turnover rate in regions of the rat brain was determined. The rats were divided into five groups: (1) control; (2) wholebody vibration (4 G, 20 Hz, 90 min) exposure alone; (3) noise [70 dB(A), 90 min] exposure alone; (4) noise [100 dB(A), 90 min] exposure alone; and (5) combined exposure for 90 min to whole-body vibration (4 G, 20 Hz) and noise [100 dB(A)]. Changes of plasma corticosterone levels were examined as indices of the pituitary-adrenal function (PAF). The whole-body vibration exposure alone caused increases in the DA turnover rate [an increase of homovanillic acid (HVA) or HVA/DA] in the frontal cortex and nucleus accumbens. Noise exposure alone caused metabolic increases in the amygdala. The combined effect of whole-body vibration and noise on the DA neuron systems suggested that the response of the PAF to the combined stimulus was greater than that to each stimulus alone.
Type of Medium:
Online Resource
ISSN:
0001-4966
,
1520-8524
Language:
English
Publisher:
Acoustical Society of America (ASA)
Publication Date:
1988
detail.hit.zdb_id:
1461063-2
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