In:
Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 137, No. 4_Supplement ( 2015-04-01), p. 2285-2285
Abstract:
This study evaluated a new ultrasound device for estimating bone mineral density (BMD) at the 1/3 radius (1/3R), as well as investigated its ability to discriminate fracture (fx) and non-fx cases. The device measures two net time delay parameters, NTDDW and NTDCW. NTDDW is the difference between transit time of an ultrasound pulse through soft-tissue, cortex and medullary cavity, and transit time through soft tissue of equal distance. NTDCW is the difference between transit time of an ultrasound pulse through soft-tissue and cortex only, and transit time through soft tissue of equal distance. The square root of the product of these two parameters is a measure of BMD at the 1/3R as measured by DXA. A clinical IRB-approved study measured 77 adults using ultrasound and DXA. An age and sex-matched subset of these subjects was used to determine the capability of DXA and ultrasound to discriminate between fx and non-fx cases. A linear regression showed that BMDUS = 0.19 * {NTDDW * NTDCW}½ + 0.28 and that the linear correlation between BMDUS and BMDDXA was 0.93 (P & lt;0.001). We found that ultrasound measurements yield results that are closely associated with those from DXA. In the case-control fx study, we found a small decrease in mean BMDDXA (1/3R) for the fx cases (P = 0.20) but a somewhat greater decrease in mean BMDUS (P = 0.05). In conclusion, the new ultrasound device should enable significant expansion of the identification of bone loss as occurs in osteoporosis and also may ultimately be able to provide additional data on fx risk.
Type of Medium:
Online Resource
ISSN:
0001-4966
,
1520-8524
Language:
English
Publisher:
Acoustical Society of America (ASA)
Publication Date:
2015
detail.hit.zdb_id:
1461063-2
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