In:
Angewandte Chemie, Wiley, Vol. 131, No. 36 ( 2019-09-02), p. 12644-12648
Abstract:
A number of new magnesium and lithium silyl reagents were prepared and shown to be outstanding nucleophiles in reactions with industrially relevant fluoroolefins. These reactions result in a net transformation of either sp 2 or sp 3 C−F bonds into C−Si bonds by two modes of nucleophilic attack (S N V or S N 2′). The methods are mild, proceeding with high chemo‐ and regioselectivity. Mechanistic pathways are described that lead to new substitution patterns from HFO‐1234yf, HFO‐1234ze, and HFO‐1336mzz, previously inaccessible by transition metal catalyzed difluorosilylation routes.
Type of Medium:
Online Resource
ISSN:
0044-8249
,
1521-3757
DOI:
10.1002/ange.v131.36
DOI:
10.1002/ange.201906825
Language:
English
Publisher:
Wiley
Publication Date:
2019
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