In:
Angewandte Chemie, Wiley, Vol. 132, No. 38 ( 2020-09-14), p. 16890-16897
Abstract:
The exceptional nature of WO 3− x dots has inspired widespread interest, but it is still a significant challenge to synthesize high‐quality WO 3− x dots without using unstable reactants, expensive equipment, and complex synthetic processes. Herein, the synthesis of ligand‐free WO 3− x dots is reported that are highly dispersible and rich in oxygen vacancies by a simple but straightforward exfoliation of bulk WS 2 and a mild follow‐up chemical conversion. Surprisingly, the WO 3− x dots emerged as co‐reactants for the electrochemiluminescence (ECL) of Ru(bpy) 3 2+ with a comparable ECL efficiency to the well‐known Ru(bpy) 3 2+ /tripropylamine (TPrA) system. Moreover, compared to TPrA, whose toxicity remains a critical issue of concern, the WO 3− x dots were ca. 300‐fold less toxic. The potency of WO 3− x dots was further explored in the detection of circulating tumor cells (CTCs) with the most competitive limit of detection so far.
Type of Medium:
Online Resource
ISSN:
0044-8249
,
1521-3757
DOI:
10.1002/ange.v132.38
DOI:
10.1002/ange.202007451
Language:
English
Publisher:
Wiley
Publication Date:
2020
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