In:
Canadian Journal of Chemistry, Canadian Science Publishing, Vol. 83, No. 8 ( 2005-08-01), p. 1120-1123
Abstract:
Ferric sulfate hydrate (Fe 2 (SO 4 ) 3 ·xH 2 O) is found to be an efficient heterogeneous catalyst for the tetrahydropyranylation of alcohols and phenols at ambient or near ambient temperature. In addition, selective monotetrahydropyranylation of symmetrical diols is achieved under similar conditions. The deprotection of THP ether and direct transformation of THP ether to the corresponding acetate by Fe 2 (SO 4 ) 3 ·xH 2 O is also studied. The simplicity of manipulation, mild conditions, reusable catalyst, good selectivity, and environment benign characters make this method a good alternative way for the THP protection of alcohols.Key words: tetrahydropyranylation, selective monotetrahydropyranylation, ferric sulfate hydrate, green chemistry.
Type of Medium:
Online Resource
ISSN:
0008-4042
,
1480-3291
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
2005
detail.hit.zdb_id:
1482256-8
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