In:
Helvetica Chimica Acta, Wiley, Vol. 90, No. 6 ( 2007-06), p. 1112-1116
Abstract:
Two new highly oxidized humulane sesquiterpenes, mitissimols F ( 1 ) and G ( 2 ), were isolated from the fruiting bodies of Lactarius mitissimus. Their structures were elucidated by using extensive spectroscopic techniques including 1D‐ and 2D‐NMR experiments. The absolute configuration of mitissimol F ( 1 ) was determined by 1 H‐NMR resolution of its diastereoisomeric α ‐methoxy‐ α ‐(trifluoromethyl)benzeneacetates (MTPA). It was shown to be (1 S ,3 E ,6 S ,8 R ,9 R ,10 S ,11 R )‐8,9 : 10,11‐diepoxy‐1,6‐dihydroxyhumul‐3‐en‐5‐one (=(1 S ,2 R ,4 R ,6 S ,8 E ,11 S ,12 R )‐6,11‐dihydroxy‐1,6,10,10‐tetramethyl‐3,13‐dioxatricyclo[10.1.0.0 2,4 ]tridec‐8‐en‐7‐one).
Type of Medium:
Online Resource
ISSN:
0018-019X
,
1522-2675
DOI:
10.1002/hlca.200790110
Language:
English
Publisher:
Wiley
Publication Date:
2007
detail.hit.zdb_id:
74-7
detail.hit.zdb_id:
1475013-2
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