In:
Journal of Heterocyclic Chemistry, Wiley, Vol. 51, No. 2 ( 2014-03), p. 513-517
Abstract:
A novel series of 2‐(5‐(4‐(1 H ‐benzo[ d ][1,2,3] triazol‐1‐yl)phenyl)‐4,5‐dihydro‐1 H ‐pyrazol‐3‐yl)phenols derivative has been synthesized from ( E )‐3‐(4‐(1 H ‐benzo[ d ][1,2,3] triazol‐1‐yl)phenyl)‐1‐(2‐hydroxyphenyl)prop‐2‐en‐1‐ones in ethanol and hydrazine hydrate under reflux condition. The synthesized compounds were screened for antibacterial activity against Gram‐positive bacteria viz Staphylococcus aureus and Bacillus subtilis and Gram‐negative bacteria viz Escherichia coli and Salmonella typhi , respectively. Some of the tested compounds showed significant antimicrobial activity. IR, 1 H NMR, mass spectral data, and elemental analysis elucidated the structures of all the newly synthesized compounds.
Type of Medium:
Online Resource
ISSN:
0022-152X
,
1943-5193
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2042274-X
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