In:
Canadian Journal of Chemistry, Canadian Science Publishing, Vol. 53, No. 7 ( 1975-04-01), p. 1051-1055
Abstract:
The heat capacity of activation for the hydrolysis of 4-methoxybenzyl trifluoroacetate in water containing 9.05 × 10 −2 mol fraction of acetone has been measured and shown to be positive. This unusual result is consistent with the notion that the ester reacts by two distinct routes: one involving acyl–oxygen fission, the other, alkyl–oxygen fission. The relative importance of the two paths for the 4-methoxy ester has been established quantitatively via a Hammett σ–ρ correlation for a series of 4-substituted-benzyl trifluoroacetates. Such an assessment allows the observed heat capacity, entropy, and enthalpy of activation to be factored into parts appropriate to each of the two reaction paths.
Type of Medium:
Online Resource
ISSN:
0008-4042
,
1480-3291
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
1975
detail.hit.zdb_id:
1482256-8
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