In:
Proteins: Structure, Function, and Bioinformatics, Wiley, Vol. 14, No. 3 ( 1992-11), p. 382-391
Abstract:
The structure of the retroviral proteinase from avian myeloblastosisassociated virus (MAV) has been determined and refined at 2.2 Å resolution. This structure is compared with those of homologous proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type 1 virus (HIV). Through comparison with the structure of a proteinase‐inhibitor complex from HIV, a model of a complex between MAV proteinase and a peptide substrate has been generated. Examination of this model suggests structural basis for the diverse specifications of viral proteinases. © 1992 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
0887-3585
,
1097-0134
DOI:
10.1002/prot.340140307
Language:
English
Publisher:
Wiley
Publication Date:
1992
detail.hit.zdb_id:
1475032-6
SSG:
12
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