In:
Plant, Cell & Environment, Wiley, Vol. 42, No. 1 ( 2019-01), p. 259-269
Abstract:
In this work, we disclose novel signatures of seed germination in the model legume Medicago truncatula , using the histone deacetylase inhibitor sodium butyrate (NaB) as stress agent. Reactive oxygen species‐independent enhancement of the antioxidant response was observed in NaB‐treated M . truncatula seeds, whereas comet assay provided evidence of DNA damage accumulation. The 3‐ureidopropionate, one of the metabolites that mostly contributed to the separation between untreated and NaB‐treated seeds, might represents a hallmark of pyrimidine degradation rising from DNA damage. Whereas metabolites resulting from DNA damage are highly conserved across animal species, their role in the plant kingdom still needs to be assessed. Interestingly, changes in the purine metabolism of NaB‐treated seeds involved N 1 ‐methyladenosine and 1‐methyl N 2 , N 2 ‐dimethylguanosine regarded as RNA modifications with regulatory roles in the eukaryotic epitranscriptome. Proper validation of these biomarkers will significantly contribute to establish new seed invigoration treatments.
Type of Medium:
Online Resource
ISSN:
0140-7791
,
1365-3040
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
391893-2
detail.hit.zdb_id:
2020843-1
SSG:
12
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