In:
FEBS Letters, Wiley, Vol. 192, No. 2 ( 1985-11-18), p. 259-262
Abstract:
The oxidation of nitroxide radicals by the reaction of hemoglobin with hydrogen peroxide occurred using both FeSO 4 and amino acids instead of hemoglobin. Tyrosine, phenylalanine, tryptophan, methionine and cysteine in globin were connected with the formation of the oxoammonium cation. Of these amino acids, tyrosine was especially effective in its oxidation. It was found that both the binding of nitroxide radicals to ferric iron and the activation of amino acids by hydroxyl radicals were important in the radical oxidation.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(85)80120-4
Language:
English
Publisher:
Wiley
Publication Date:
1985
detail.hit.zdb_id:
1460391-3
SSG:
12
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