In:
The Journal of Physiology, Wiley, Vol. 599, No. 11 ( 2021-06), p. 2907-2932
Abstract:
TMS is commonly used to study excitatory/inhibitory neurotransmission in cortical circuits. Changes in cortical excitability following TMS are typically measured from hand (using EMG; limited to motor cortex) or scalp (using EEG); however, it is unclear whether these two measures represent the same activity when assessing motor cortex. We found that TMS‐EMG and TMS‐EEG measures of motor cortex excitability are differentially affected by sensory confounds at different time points, masking any actual relationship between them in the time domain. In the frequency domain, local high‐frequency oscillations in EEG recordings were minimally confounded by sensory artefacts and demonstrated strong correlations with EMG measures of cortical excitability across time, regardless of TMS intensity or waveform. Therefore, despite the effects of sensory artefacts, the two measures of motor cortex excitability share a response component, suggesting that they index a similar cortical activity and perhaps the same neuronal population.
Type of Medium:
Online Resource
ISSN:
0022-3751
,
1469-7793
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
1475290-6
SSG:
12
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