In:
Zeitschrift für Naturforschung C, Walter de Gruyter GmbH, Vol. 78, No. 5-6 ( 2023-05-25), p. 179-187
Abstract:
In the course of finding new antifungal natural compounds against plant pathogens, the methanol extract of Desmodium triflorum was investigated phytochemically. From n -butanol-soluble fraction, seven compounds ( 1 – 7 ) were isolated and structurally elucidated. Of which, six compounds belong to flavone 6- or 8- C -glycoside class ( 1 – 6 ). Three major compounds ( 1 – 3 ) exhibited moderate in vitro antifungal activity against Sclerotium rolfsii , Fusarium oxysporum f. sp. cubense , and Phytophthora palmivora. Compound 1 (IC 50 = 162.1 μg/mL) was most active against S. rolfsii in a dose-dependent manner. At 300 μg/mL, compounds 1 and 2 significantly inhibited P. palmivora , whereas compound 3 lacked effectiveness. In addition, the nanoemulsion of the methanol extract with a droplet size of 12.2 nm displayed an excellent inhibition against S. rolfsii and P. palmivora compared with the normal extract. The presence of 1 (0.846%) and 2 (0.759%) in the methanol extract may attribute to the antifungal activity of D. triflorum . These results proved the potential of D. triflorum and its C-glycoside flavonoids against phytopathogenic fungi for the first time. Besides, an enhancement in the effectiveness of nanoemulsion containing D. triflorum extract against the fungi was confirmed. The structural characteristics of 1 and 2 could be considered to develop new fungicidal substances in the future.
Type of Medium:
Online Resource
ISSN:
0939-5075
,
1865-7125
DOI:
10.1515/znc-2022-0048
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2023
detail.hit.zdb_id:
2078107-6
SSG:
12
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