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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 6 (1983), S. 101-107 
    ISSN: 1573-2630
    Keywords: choroid ; retina ; vascular permeability ; temperature control ; nutrition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The choroidal vascular bed has many interesting features such as relatively wide but flat capillaries, fenestrated capillary walls and an enormous blood flow. The high flow rate results in a high oxygen tension in the tissue and is also of importance in the temperature control of the eye. The capillary wall is permeable to plasma proteins which is probably of great importance for the supply of vitamin A to the pigment epithelium. The permeability to low molecular weight substances is very high which results in a tissue fluid similar to plasma with respect to small molecules. It is not clear whether the choriocapillaris is normally reabsorbing fluid transported into the choroid from the retina and from the anterior chamber or if there is a net filtration from the choriocapillaris. Fluid can pass from the choroid through the suprachoroid into the episcleral tissues via the scleral substance and spaces around the blood vessels and nerves.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2013-08-09
    Description: Integrated Ocean Drilling Program (IODP) Expedition 334 to southern Costa Rica, Central America, documented unprecedented subduction erosion in an area of active seismic slip. Widespread subduction erosion of the upper plate initiated when the Cocos Ridge, an overthickened aseismic ridge, arrived at the Middle America Trench. Subduction erosion was coeval with the rapid formation of deposition centers on the forearc of the upper plate. The completely recovered shelf sequence constrains a short (〈2 m.y.) interval of extreme subsidence (~1200 m) with a rapid pulse occurring during the first ~0.3 m.y. This event removed an estimated 1.2 x 10 6 km 3 of forearc material at a rate of ~1690 km 3 /m.y./km of trench during a time of rapid (~1035 m/m.y.) shelf sediment accumulation. At this erosive margin, a sediment-starved trench persisted, in spite of abundant sediment supply, because subduction erosion led to the creation of forearc basins. Similar rapid pulses of subduction erosion may punctuate the evolution of many margins, contributing disproportionately to crustal recycling at subduction zones with implications for the evolution of continental crust and mountain belts, and recycling of continental material into the mantle.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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  • 3
    Publication Date: 2017-12-27
    Description: Bullous pemphigoid (BP) is the most common autoimmune blistering disease, and it features itchy oedematous erythemas and tense bullae on the whole body most commonly in the elderly. BP180 is the most common autoantigens of BP, and BP230 is the only target of autoantibodies in approximately 8% of patients with BP 1 . It has been reported that elderly patients with BP sometimes have comorbidities associated with neurological disease (ND) including dementia 2 . BP antigens and their isoforms can be identified in skin as well as in neuronal tissues, suggesting that exposure of the neuronal antigen may lead to an immune reaction against the epithelial isoform 3 . Here, we describe two elderly cases of BP with dementia in which the autoantibodies reacted to BP230 but not to BP180 (BP230-BP). This article is protected by copyright. All rights reserved.
    Print ISSN: 0007-0963
    Electronic ISSN: 1365-2133
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 4
    Publication Date: 2017-09-03
    Description: Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease targeting various autoantigens, including the C-terminus of collagen XVII (COL17) and laminin332. Bullous pemphigoid (BP) is the most common autoimmune blistering disease, affecting the mucosae in 10-20% of cases. COL17, particularly, the non-collagenous (NC)16A domain is the pathogenic epitope for BP. This article is protected by copyright. All rights reserved.
    Print ISSN: 0007-0963
    Electronic ISSN: 1365-2133
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 5
    Publication Date: 2015-01-21
    Description: The very large slip on the shallow portion of the subduction interface during the 2011 Tohoku-oki earthquake (M w 9.0) caused a huge tsunami along the northeast coast of Honshu, Japan. In order to elucidate the mechanics of such tsunamigenic slip, the Integrated Ocean Drilling Program Expedition 343 (Japan Trench Fast Drilling Project, JFAST), was carried out one year after the earthquake and succeeded in recovering rocks constituting the active plate boundary fault. Our mineralogical analyses using X-ray diffraction reveal that the shallow portion of the fault zone that caused the earthquake is significantly enriched in smectite compared to the surrounding sediments, which may be intimately linked to the tsunamigenic shallow faulting. For comparison, we also analyzed mineralogical features of incoming sediments just prior to subduction, recovered on the outer rise of the Japan Trench (Site 436, Deep Sea Drilling Project Leg 56), and found a characteristic smectite-rich horizon in the uppermost ~5 m of the pelagic clay layer. This horizon should be mechanically weak and will become the future plate boundary fault, as observed in the JFAST cores. The smectite-rich deposits are broadly distributed in the northwestern Pacific Ocean, and may therefore potentially enhance conditions for large shallow slip during earthquakes that occur over a broad area of the Japan Trench plate boundary, which would result in large tsunamis for this region.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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  • 6
    Publication Date: 2015-05-23
    Description: Mycosis fungoides (MF), the most common cutaneous T-cell lymphoma, usually progresses slowly but can involve multiple organs, such as the lung and spleen, at an advanced stage. 1 Here, we report an unusual case of MF associated with splenic infarction due to MF invasion that was histologically confirmed in life. A 72-year-old man had suffered from multiple asymptomatic brownish-red scaly macules, plaques and nodules on the extremities for 5 years without any extracutaneous lesions or internal involvement, as confirmed by CT scan and bone marrow biopsy. This article is protected by copyright. All rights reserved.
    Print ISSN: 0007-0963
    Electronic ISSN: 1365-2133
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 7
    Publication Date: 2020-02-12
    Description: The Costa Rica Seismogenesis Project (CRISP) is an experiment to understand the processes that control nucleation and seismic rupture of large earthquakes at erosional subduction zones. Integrated Ocean Drililng Program (IODP) Expedition 334 by R/V JOIDES Resolution is the first step toward deep drilling through the aseismic and seismic plate boundary at the Costa Rica subduction zone offshore the Osa Peninsula where the Cocos Ridge is subducting beneath the Caribbean plate. Drilling operations included logging while drilling (LWD) at two slope sites (Sites U1378 and U1379) and coring at three slope sites (Sites U1378–1380) and at one site on the Cocos plate (Site U1381). For the first time the lithology, stratigraphy, and age of the slope and incoming sediments as well as the petrology of the subducting Cocos Ridge have been characterized at this margin. The slope sites recorded a high sediment accumulation rate of 160–1035m m.y.-1 possibly caused by on-land uplift triggered by the subduction of the Cocos Ridge. The geochemical data as well as the in situ temperature data obtained at the slope sites suggest that fluids are transported from greater depths. The geochemical profiles at Site U1381 reflect diffusional communication of a fluid with seawater-like chemistry and the igneous basement of the Cocos plate (Solomon et al., 2011; Vannucchi et al., 2012a). The present-day in situ stress orientation determined by borehole breakouts at Site U1378 in the middle slope and Site U1379 in the upper slope shows a marked change in stress state within ~12 km along the CRISP transect; that may correspond to a change from
    Language: English
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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