ISSN:
1573-7217
Keywords:
breast cancer
;
EGF receptor
;
estrogen receptor
;
histologic grade
;
progesterone receptors
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Steroid receptors (ER, PR) and EGF-receptor were determined on 177 loco-regional primary breast cancers. Binding assay for EGF receptor was performed using a single saturating concentration of125I-EGF incubated with membranes in the presence or absence of unlabeled EGF. With threshold values of 5 fmol/mg and 10 fmol/mg for EGF-R and steroid receptors respectively, we noted an inverse relationship between the expression of EGF-R, and ER and PR. EGF-R expression is decreased with tumor differentiation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01809293
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