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  • 1
    Electronic Resource
    Electronic Resource
    HLA- DR typing in 58 cases of rheumatoid arthritis (1982)
    Springer
    Clinical rheumatology 1 (1982), S. 112-116 
    Details
    ISSN: 1434-9949
    Keywords: HLA-DR ; Rheumatoid Arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The results of a previous study led us to believe that the association of HLA-DR4 and rheumatoid arthritis could be of particular interest in our region. In this work we typed 58 caucasoid patients in the Marseilles area by microlymphocytotoxicity assay in B-cells. HLA-DR4 was found to be at the same level as that observed by the authors in the 8th Workshop of histocompatibility (1980) (X2: 32.36, P (0.001) and very high in the seropositive patients (61.5 per cent). No correlation with sex was observed. We again found a low frequency of HLA-DR4 (15.8 per cent) in our controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02275600
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    IgM antiplatelet antibodies in 7 out of 20 rheumatoid arthritis sera. A new antiplatelet antibody ELISA. Reverse correlation with anti-B-lymphocyte antibodies in the same sera (1986)
    Springer
    Clinical rheumatology 5 (1986), S. 189-192 
    Details
    ISSN: 1434-9949
    Keywords: Rheumatoid Arthritis ; Antiplatelet Antibodies ; ELISA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a previous work, we had found that anti-B lymphocyte antibodies exist in rheumatoid arthritis. To investigate whether these antibodies were directed against surface immunoglobulins or not we have investigated if RA sera could recognize similar structures on other targets such as platelets (on which immunoglobulins and immune complexes are present) by a new ELISA method. No IgG antiplatelet antibody was found in 20 RA sera. But 7 out these 20 RA sera had IgM antiplatelet antibodies when tested on platelets from 5 donors. The comparison of the positivities of these sera on B lymphocytes and platelets from the same donors showed a statistically significant reverse (X2=20,008, p〈0.0001) correlation. The target antigen and the meaning of these IgM antiplatelet antibodies, which seem to be associated with severe RA, is still under investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02032356
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Magneic resonance imaging of the wrist in rheumatoid arthritis: Comparison with other inflammatory joint diseases and control subjects (1996)
    Springer
    Clinical rheumatology 15 (1996), S. 137-142 
    Details
    ISSN: 1434-9949
    Keywords: Magnetic Resonance Imaging ; Rheumatoid Arthritis ; Wrist ; Joint Erosions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aim of this study was to evaluate magnetic resonance images (MRI) of the wrist of rheumatoid arthritis (RA) patients. MRI and plain X-ray of the wrists were performed in 15 patients with RA, 7 patients with another chronic inflammatory joint disease (CIJD), and 10 control subjects. Patients had only minor changes on plain X-ray. Coronal T1 weighted spin echo sequences were performed before and after an intravenous pulse of gadolinium (GD). Contiguous 3 mm thick slices were obtained. Synovitis was frequently objectivized in the two groups of patients. MRI detected far more erosions and central bone geodes than plain X-ray. Geodes were frequent among controls while cortical bone erosions were frequent in patients. Most of the erosions were enhanced after GD injection in the RA patients but not in the 2 other groups. Thus MRI is not only useful in diagnosing inflammatory changes of the wrist but also in distinguishing early stage RA from other CIJD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02230330
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  • 4
    Electronic Resource
    Electronic Resource
    Monocytes and granulocytes in rheumatoid arthritis (RA): phagocytic activity and superoxide anion production (1985)
    Springer
    Clinical rheumatology 4 (1985), S. 433-440 
    Details
    ISSN: 1434-9949
    Keywords: Granulocytes ; Monocytes ; Rheumatoid Arthritis ; Phagocytosis ; Oxidative Burst
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary It is suggested by many tests that phagocytic cells were implied in inflammation which occurred during rheumatoid arthritis (RA). Further, three subject populations were selected for this study: — Rheumatoid arthritis patients diagnosed according to American Rheumatism Association criteria (ARA mean=6) and treated with gold compounds. — Control subjects treated with the same non-steroidal anti-inflammatory drug (NSAID), diclofenac (75 mg per day). — Normal subjects without disease or treatment. Blood granulocytes and monocytes were separately tested for ingestion of three different particle species (opsonized zymosan, immunoglobulin G sheep red cells, glutaraldehyde-treated sheep red cells) and stimulation of Superoxide anion production by these particles. All phagocytic cells in RA patients have normal phagocytic response and Superoxide anion production. Autologous serum does not inhibit the activity of these cells. In addition the NSAID (diclofenac) does not act upon phagocytosis and oxidative burst of control cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02031896
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    Paper (German National Licenses)
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