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  • PACS. 61.25.Hq Macromolecular and polymer solutions; polymer melts; swelling - 83.70.Hq Heterogeneous liquids: suspensions, dispersions, emulsions, pastes, slurries, foams, block copolymers, etc.  (1)
  • Risk Factors, Genetic, Association Studies, Ischemic Stroke  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Random copolymers at a selective interface: Many chains with excluded volume interactions (1999)
    Springer
    The European physical journal 8 (1999), S. 73-79 
    Details
    ISSN: 1434-6036
    Keywords: PACS. 61.25.Hq Macromolecular and polymer solutions; polymer melts; swelling - 83.70.Hq Heterogeneous liquids: suspensions, dispersions, emulsions, pastes, slurries, foams, block copolymers, etc.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: We investigate numerically, using the bond-fluctuation model, the adsorption of many random AB-copolymers with excluded volume interactions at the interface between two solvents. We find two regimes, controlled by the total number of polymers. In the first (dilute) regime, the copolymers near the interface extend parallel to it, while in the second regime they extend perpendicular to it. The density at the interface and the density in the bulk depend differently on the total number of copolymers: In the first regime the density at the interface increases more rapidly than in the bulk, whereas the opposite is true in the second regime.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100510050670
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    Paper (German National Licenses)
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  • 2
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    Homozygous ALDH2*2 Is an Independent Risk Factor for Ischemic Stroke in Taiwanese Men [Clinical Sciences] (2016)
    American Heart Association (AHA)
    In: Stroke
    Details
    Publication Date: 2016-08-23
    Description: Background and Purpose— The * 2 allele of the aldehyde dehydrogenase 2 gene (ALDH2 ) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was associated with hypertension and ischemic stroke. This study intended to further investigate whether the above variant of ALDH2 increases the risk for ischemic stroke in Taiwanese. Methods— A case–control study was conducted on 914 patients with acute ischemic stroke and 746 nonstroke controls. Polymerase chain reaction and sequencing were used to identify the ALDH2 genotype. Vascular risk factors, stroke subtypes, vascular stenosis, and stroke outcomes were analyzed. Results— ALDH2 genotypes differed significantly between male controls (* 1/*1 versus * 1/*2 versus * 2/*2 =53.8% versus 39.9% versus 6.4%) and male patients with ischemic stroke (* 1/*1 versus * 1/*2 versus * 2/*2 =51.5% versus 37.3% versus 11.2%; P =0.048). No significant difference was found between groups for female patients ( P =0.228). Multivariate logistic regression analysis revealed that the ALDH2*2/*2 genotype was an independent risk factor for ischemic stroke in male patients (odds ratio, 1.93 [95% confidence interval, 1.07–3.46]; P =0.028). Further analysis of men with ischemic stroke demonstrated that the polymorphism of ALDH2 was not related to vascular risk factors, severity of vascular atherosclerosis, stroke subtypes, and stroke functional outcomes. Conclusions— The study demonstrated that ALDH2*2/*2 may be an independent risk factor for ischemic stroke in Taiwanese men, but not in Taiwanese women.
    Keywords: Risk Factors, Genetic, Association Studies, Ischemic Stroke
    Print ISSN: 0039-2499
    Electronic ISSN: 1524-4628
    Topics: Medicine
    Published by American Heart Association (AHA)
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