ISSN:
1432-0878
Keywords:
Duodenum
;
Guinea-pig
;
Organ culture
;
Fine structure
;
Light- and Electron microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The fine structure of adult guinea-pig duodenum maintained in organ culture for 24 to 48 hours has been analysed. During the first 24 hours, the absorptive cells of the villi remain unchanged with a normal distribution of their organelles. The undifferentiated cells of the crypts are generally well preserved but several zones exhibit cellular injury. After 48 hours, necrosis is present in the crypts and the absorptive cells of the villi show numerous signs of degeneration. Short time metabolic studies are possible with this model.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00582792
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