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  • 1
    Electronic Resource
    Electronic Resource
    Beeinflussung der Noradrenalinabgabe aus isolierten Kaninchenherzen durch Β-Adrenolytica unter sympathischer Nervenreizung (1971)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 268 (1971), S. 102-113 
    Details
    ISSN: 1432-1912
    Keywords: Β-Receptor Blocking Drugs ; Isolated Rabbit Heart ; Noradrenaline Output ; Noradrenaline Uptake ; Β-Adrenolytika ; Isoliertes Kaninchenherz ; Noradrenalinabgabe ; Noradrenalinaufnahme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using isolated rabbit hearts with sympathetic nerve supply we have studied the influence of LB 46, (−)- and (+)-INPEA, (−) and (+)-propranolol on the output of noradrenaline evoked by electrical stimulation of the sympathetic nerves. 1. LB 46, (−)-INPEA and the optical isomers of propranolol, drugs with differentΒ-receptor blocking potency, increase the noradrenaline output induced by electrical nerve stimulation. 2. Likewise, (+)-INPEA, which lacksΒ-receptor blocking activity, enhances the noradrenaline output to the same extent as theΒ-receptor blocking (−)-isomer. 3. High concentrations of both optical isomers of propranolol have a cardiodepressant action; they do not further augment the noradrenaline output but inhibit it. 4. Additional experiments with the optical isomers of INPEA show an inhibition by these drugs of the uptake of noradrenaline by the rabbit heart. The latter observation favours the hypothesis that all drugs tested increase the noradrenaline output by an inhibition of re-uptake. The ability of these drugs to inhibit the noradrenaline re-uptake is independent of theirΒ-receptor blocking action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00997177
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of phentolamine on noradrenaline uptake and release (1971)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 271 (1971), S. 181-192 
    Details
    ISSN: 1432-1912
    Keywords: Isolated Rabbit Heart ; Phentolamine ; Adrenergic Fibres ; Noradrenaline Liberation ; Noradrenaline Binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The influence of phentolamine on the uptake of exogenous noradrenaline infused into the aortic cannula and on the overflow of endogenous noradrenaline caused by sympathetic nerve stimulation was investigated in the isolated perfused rabbit heart. 10−6 M phentolamine doubled the overflow of endogenous noradrenaline, but did not change noradrenaline uptake. 10−5 M phentolamine increased the stimulation-induced overflow of noradrenaline 4-fold and inhibited amine uptake by about 50%. 10−4 M phentolamine elevated the overflow of noradrenaline less than 10−5 and 3×10−5 M did. The augmentation of transmitter overflow was only partly reversed by 13 min perfusion with drug-free medium. Pretreatment of hearts with 1.5×10−5 M cocaine or with 10−7 or 10−6 M desipramine did not change the effect of phentolamine on the overflow of noradrenaline evoked by nerve impulses. Pretreatment of hearts with 10−5 M, but not with 10−6 M, phentolamine prevented the increase of transmitter overflow by cocaine. It is concluded that low concentrations of phentolamine potentiate the overflow of noradrenaline during nerve stimulation by a mechanism different from that of cocaine, i.e. different from inhibition of neuronal re-uptake. The nature of this mechanism is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00998579
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    Paper (German National Licenses)
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  • 3
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    Phonon pressure coefficients and deformation potentials of wurtzite AlN determined by uniaxial pressure-dependent Raman measurements (2014)
    American Physical Society (APS)
    Details
    Publication Date: 2014-11-08
    Description: Author(s): G. Callsen, M. R. Wagner, J. S. Reparaz, F. Nippert, T. Kure, S. Kalinowski, A. Hoffmann, M. J. Ford, M. R. Phillips, R. F. Dalmau, R. Schlesser, R. Collazo, and Z. Sitar We studied bulk crystals of wurtzite AlN by means of uniaxial pressure-dependent Raman measurements. As a result, we derive the phonon pressure coefficients and deformation potentials for all zone center optical phonon modes. For the A1 and E1 modes, we further experimentally determined the uniaxial... [Phys. Rev. B 90, 205206] Published Fri Nov 07, 2014
    Keywords: Semiconductors I: bulk
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 4
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    Optical signatures of nitrogen acceptors in ZnO (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-06-22
    Description: Author(s): S. Lautenschlaeger, S. Eisermann, G. Haas, E. A. Zolnowski, M. N. Hofmann, A. Laufer, M. Pinnisch, B. K. Meyer, M. R. Wagner, J. S. Reparaz, G. Callsen, A. Hoffmann, A. Chernikov, S. Chatterjee, V. Bornwasser, and M. Koch We report on the optical properties of nitrogen acceptor-doped ZnO epilayers in the medium and high doping regimes using temperature and excitation power-dependent, as well as time-resolved photoluminescence experiments. The epilayers were doped with ammonia during homoepitaxial growth on ZnO single... [Phys. Rev. B 85, 235204] Published Thu Jun 21, 2012
    Keywords: Semiconductors I: bulk
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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