ISSN:
1438-8359
Keywords:
Propofol
;
Dog
;
Histamine
;
Intravenous anaesthetic
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We examined a property of emulsion formation of propofol (ICI 35868) to release histamine into circulating plasma in dogs. Plasma histamine was measured with radioimmunoassay before (baseline), and 1, 5 and 10 min after the administration of 15 mg·kg−1 propofol. There were no significant differences between the plasma histamine levels at 1, 5 and 10 min after the administration of propofol and the baseline level. We conclude that the emulsion formation of propofol of 15 mg·kg−1 does not release histamine during induction of anesthesia in dogs. (Mitsuhata H, Shimizu R: Plasma histamine levels during induction of anesthesia with propofol in dogs. J Anesth 7: 206–209, 1993)
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s0054030070206
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