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Burst-stimulating activity in sera of patients with polycythemia vera (1982)

Essers, U. ; Niedeggen, A. ; Heilmann, E. ; [et al.]

Springer

Annals of hematology 45 (1982), S. 103-108

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ISSN: 1432-0584

Keywords: Polycythemia vera ; Stem cell growth ; Hormonal regulation ; Burst stimulating activity

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Sera from patients with polycythemia vera without prior cytostatic therapy stimulate the growth of bursts during in vitro methylcellulose cultures of peripheral mononuclear cells from normal donors. Sera from patients with polycythemia vera in remission after treatment with 32P or cyclophosphamid, did not significantly stimulate the growth of bursts during incubation with normal peripheral mononuclear cells. The stimulating factor was demonstrable again in patients during relapse.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00319937

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