GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Heart transplantation, dogs  (1)
  • Key words Spondylolysis  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Spondylolysis and spondylolisthesis: correlation with sport (1997)
    Springer
    Der Orthopäde 26 (1997), S. 755-759 
    Details
    ISSN: 1433-0431
    Keywords: Key words Spondylolysis ; Spondylolisthesis ; Etiology ; Therapy ; Exercise tolerance ; Schlüsselwörter Spondylolyse ; Spondylolisthese ; Ursache ; Therapie ; Belastbarkeit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Spondylolyse und Spondylolisthese treten vorwiegend im unteren Lendenwirbelbereich auf. Neben angeborenen Schäden als Ursache der Spondylolyse ist der Zusammenhang einer erhöhten Spondylolyseinzidenz bei leistungssportlicher Belastung belegt. Im Frühstadium kommt es unter konservativer Therapie (Sportpause für 3 Monate, Lendenstützmieder) zur Ausheilung. Beschwerdepersistenz, neurologische Ausfälle und Progredienz des Wirbelgleitens erfordern operative Maßnahmen (Isthmusrekonstruktion oder dorsoventrale Spondylodese). Die sportliche Belastbarkeit ist abhängig vom Ausmaß der Instabilität, der Progredienz des Wirbelgleitens und den Beschwerden. Die Belastbarkeitsgrenze ist persönlichkeitsabhängig und erfordert individuelle Entscheidungen des Arztes. Rückenschwimmen, kräftigende Übungen für die Bauch- und Rückenmuskulatur sowie Sportarten mit gleichmäßigen Bewegungsabläufen sind zu empfehlen. Bei stabilen Spondylolysen und Spondylolisthesen ohne ungünstige Begleitfaktoren ist Schulsport uneingeschränkt möglich.
    Notes: Summary Spondylolysis and spondylolisthesis occur predominantly in the lower lumbar spine. Besides congenital defects such as predisposition of spondylolysis the correlation between competitive sports activities and an increased incidence of spondylolysis is proved. In early stages, complete healing can be achieved by conservative treatment (abstinence from sports activities for 3 months, orthesis). Persistence of pain, neurologic symptoms and progression of vertebral slipping are indications for operative treatment (reconstruction of the isthmus, dorso-ventral spondylodesis). The exercise tolerance depends on the extent of instability, progression of vertebral slipping and clinical symptoms. The limits of exercise tolerance vary among the individual athletes and require the decision of the physician. Backstroke swimming, abdominal and back muscle strengthening exercises, and types of sport involving smooth movements are advisable. Sports education in school is possible without restriction in patients with stable spondylolysis and in those with spondylolisthesis without unfavourable concomitant factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00003437
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Intragraft events after heart transplantation: an experimental study comparing cytology in coronary sinus blood, peripheral blood, and daily histology (1994)
    Springer
    Transplant international 7 (1994), S. 22-26 
    Details
    ISSN: 1432-2277
    Keywords: Heart transplantation, dogs ; Rejection, heart
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Acute rejection is a frequent consequence after heart transplantation. To expand our knowledge of the rejection process and to investigate some intragraft events during acute rejection, the following experimental transplantation model was designed. Right cervical heart transplantation was performed in 12 mongrel dogs. Two experimental groups of six animals each received different immunosuppressive regimens. All animals were treated with daily triple drug therapy. In contrast to group 1, the animals in group 2 received high-dose steroids during rejection. The condition of the hearts was examined by daily transmural biopsies, graded according to the Billingham classification. To detect and quantify alterations in the mononuclear cell subsets of the myocardial venous return, blood samples from the coronary sinus blood (CS) and from peripheral blood (PB) were taken simultaneously with the biopsy. The total number of lymphoblasts and activated lymphocytes was determined and an activation index (AI) was calculated. The data referred to was established from 337 transmural biopsies. The AI of PB (n=287) correlated well with the different stages of acute rejection (grade B0: AI=2.2±2.1; grade B1+2: AI=6.3±1.7; grade B3: AI=10.0±4.7; P〈0.001). The rejection kinetics of both groups, including the rejection-free interval following high-dose steroid administration in group 2, could be expressed accurately by the AI. The time course of the total number of lymphoblasts in CS versus PB demonstrated that the lymphoproliferative response started 4 days prior to the first intramyocardial signs of rejection (x = 3.8 ± 0.7; n=12). The maximum number of lymphoblasts was seen on the day of rejection in group 1 and 1 day after the onset of histologically proven rejection in group 2 (group 1: n=6: CS x = 40.1 ± 7.5; PB x = 12.2 ± 4.1; P〈0.001; group 2: n=6: CS x = 39.4 ± 8.8; PB x = 12.9 ± 3.7; P〈0.001). Under rejection therapy in group 2 these cells decreased immediately, followed by a short rejection-free interval. In group 1 the total number of lymphoblasts diminished continuously, almost reaching the nuber in PB at the time of final rejection. In contrast, activated lymphocytes did not render adequate results. Comparison of daily histology and the data of PB proved there is a good correlation between the AI and the different histologic stages of acute rejection. The total number of lymphoblasts in CS during rejection is significantly higher than in PB. Acute rejection seems to be detectable almost 4 days before histology and PB cytology by cytologic evaluation of the CS. Therefore, we speculate that the differentation and proliferation of lymphoblasts during the initial phase of acute rejection takes place within the graft itself.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335659
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...