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  • 1
    Electronic Resource
    Electronic Resource
    Endogenous gibberellins and inhibitors in caryopses of rye
    Amsterdam : Elsevier
    Phytochemistry 17 (1978), S. 963-966 
    Details
    ISSN: 0031-9422
    Keywords: 4'-dihydrophaseic acid ; ABA ; GC-MS. ; Gramineae ; Secale cereale ; caryopses ; gibberellins ; identification
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)88657-4
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Über die Aufnahme des Psychopharmakons Imipramin in das Rattenhirn und seinen Metabolismus bei einmaliger und bei chronischer Gabe des Medikamentes (1969)
    Springer
    Psychopharmacology 14 (1969), S. 74-82 
    Details
    ISSN: 1432-2072
    Keywords: Imipramine ; Metabolism ; Brain ; Rats ; Single Dose-Chronic Dose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A method is given for extraction and quantitative determination of imipramine (Tofranil®) and some of its metabolites in the brain tissue. The recovery of imipramine added to brain tissue/amount extracted from the brain was determined for imipramine, desmethylimipramine, didesmethylimipramine and iminodibenzyl. The uptake and metabolism of imipramine in the rat brain were determined after administration of a single dose. The imipramine level in the brain reached a maximum one hour after i.p. administration, whereas after subcutaneous injection the maximum is only reached after 2 hours. In either case only 0.2% of the imipramine given is absorbed by the brain. In none of the cases were metabolites of imipramine found after the short time tests. In contrast to imipramine, desmethylimipramine (Pertofran®) is found in the rat brain only after a long period (4 hours). No accumulation of the drug in the brain was observed after daily administration of imipramine for 10 days and under the test conditions mentioned. A level, amounting to 2 μg imipramine/brain, is reached as early as the first day of administration. Desmethylimipramine appeared for the first time on the third test day, and its level remained practically unchanged from the third to the tenth day at 1 μg/brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00401536
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Gibberellins in Gramineae (1993)
    Springer
    Plant growth regulation 12 (1993), S. 91-98 
    Details
    ISSN: 1573-5087
    Keywords: gibberellins ; uccurrence ; glucose conjugates ; Gramineae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Data on the occurrence of free and conjugated gibberellins in different tribes of Gramineae are compiled and discussed with regard to their biosynthetic pathways. From the gibberellins detected so far the functioning of both the early 13-hydroxylation and the non-3,13-hydroxylation pathway of GA biosynthesis in gramineous plants can be deduced and the discovery of further gibberellin conjugates may be expected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00144588
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  • 4
    Electronic Resource
    Electronic Resource
    Nuclear medicine liver-function tests for pregnant women and children (1985)
    Springer
    European journal of nuclear medicine 11 (1985), S. 58-61 
    Details
    ISSN: 1619-7089
    Keywords: Children ; Diagnostic techniques ; Diseases ; Drugs ; Function tests ; Isotope applications ; Liver ; Metabolism ; Nitrogen-15 ; Pregnant women ; Stable isotopes ; Urine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A simple, non-invasive, non-radioactive liverfunction test is proposed. After an oral dose of 3 mg 15N-methacetin per kilogram body mass, the kinetics of 15N excretion via urine were characterized by the quotient of the amounts of 15N excreted in two successive urine samples (Q value). The stable nitrogen isotope 15N was found to be an excellent and easily detectable indicator of the sum of all methacetin metabolites present in urine. Alterations in the nature or ratio of methacetin metabolites due to liver diseases could not be found. From the investigation of 11 men, 3 pregnant women and 15 children, a clear difference was observed in Q values of healthy persons and patients suffering from liver-cell-activity diseases. The discriminating power of our new liver-function test is shown to be equivalent to that of the 14CO2 breath test.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252133
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    Paper (German National Licenses)
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