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  • Gossypol  (1)
  • Light and electron microscopy  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Ultrastructural investigation of the postnatal development of the hamster harderian gland (1973)
    Springer
    Cell & tissue research 142 (1973), S. 1-12 
    Details
    ISSN: 1432-0878
    Keywords: Harderian gland ; Hamster ; Sexual dimorphism ; Alveolar cells ; Light and electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The lobules of the Harderian glands of young male and female hamsters are widely separated by connective tissue and are made up of alveolar cells containing small vacuoles. There is considerable increase in the size of the lobules by 12 days. Based on size distribution of vacuoles two types of alveolar cells can be recognized in the male hamsters 4 weeks and older. The Harderian glands of 2-week animals of both sexes contain a black-brown pigment. The appearance of pigment is accompanied by a proliferation of membranes. In the female the amount of pigment increases with increasing age until 4 weeks of age and then remains at a relatively stable level. In the male no pigment was found after 4 weeks of age. Membrane-bounded juxtanuclear structures are present in the alveolar cells of both sexes until 3 weeks of age. These structures appear to play different roles in the male and female hamsters. The differentiation of the alveolar cells into light and dark types must take place during the 3rd week of postnatal development. A possible relationship between the levels of gonadal hormones and the occurrence of pigment at different ages in both sexes is also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306700
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of ingested gossypol on the ultrastructure of rat ovarian follicles (1987)
    Springer
    Cell & tissue research 250 (1987), S. 215-220 
    Details
    ISSN: 1432-0878
    Keywords: Gossypol ; Ovarian follicle ; Granulosa cells ; Lysosomes ; Smooth endoplasmic reticulum ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Ultrastructural changes were observed in the oocytes and granulosa cells of the ovarian follicles of sexually mature female rats treated daily for 60 days with gossypol acetic acid at a dosage known to induce sterility in male rats (20 mg/kg body weight, orally). The changes included an increased lysosomal population in the ooplasm and a reduced, poorly developed smooth endoplasmic reticulum in the granulosa cells. The latter changes suggest a suppression of the secretory activity of the granulosa cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214674
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    Paper (German National Licenses)
    Fulltext
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