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Global Nuclear Energy Partnership. (2009)

Bernstein, Alan N.

Hauppauge :Nova Science Publishers, Incorporated,

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Schlagwort(e): United States. -- Dept. of Energy -- Rules and practice. ; Reactor fuel reprocessing -- Waste disposal -- United States. ; Radioactive waste disposal -- United States. ; Spent reactor fuels -- Storage -- United States. ; Radioactive waste repositories -- United States. ; Electronic books.

Materialart: Online-Ressource

Seiten: 1 online resource (61 pages)

Ausgabe: 1st ed.

ISBN: 9781613249567

URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=3019828

DDC: 333.7924153

Sprache: Englisch

Anmerkung: Intro -- GLOBAL NUCLEAR ENERGYPARTNERSHIP -- GLOBAL NUCLEAR ENERGYPARTNERSHIP -- CONTENTS -- PREFACE -- RESULTS IN BRIEF -- BACKGROUND -- Materials in Spent Nuclear Fuel -- Technologies for Recycling Spent Nuclear Fuel -- DOE'S ORIGINAL ENGINEERING-SCALEAPPROACH WOULD MEET GNEP'SOBJECTIVES IF ADVANCED RECYCLINGTECHNOLOGIES ARE SUCCESSFULLYDEVELOPED -- Successful Development of Advanced RecyclingTechnologies Would Be an Initial Step toward GreatlyExtending the Capacity of a Geologic Repository -- Advanced Recycling Technologies Envisioned underDOE's Original Approach to GNEP Pose LowerProliferation Risks Than Existing Recycling Technologies -- Lack of Industry Participation Could Reduce theProspects for Commercialization and Widespread Use ofAdvanced Recycling Technologies -- DOE's Original Approach to GNEP Included Building aSeparate Engineering-Scale Reprocessing Plant beforeConducting R& -- D that Would Help in Designing the Plant -- The R& -- D Facility and Advanced Reactor Would EnableDOE to Develop the Advanced Recycling TechnologiesEnvisioned under Its Original Approach to GNEP -- DOE'S ACCELERATED APPROACH WOULDLIKELY RELY ON TECHNOLOGIES THAT FALLSHORT OF MEETING GNEP'S OBJECTIVES -- Two Other Industry Consortia Proposed to AddressGNEP's Objectives by Using Technologies That Are NotMature Enough for Commercial Deployment -- The Government Would Likely Bear Substantial Costsfor Commercial-Scale Recycling Facilities -- DOE Officials Recognize the Limitations of AcceleratingDeployment of Commercial-Scale Facilities but CiteOther Benefits -- CONCLUSIONS -- RECOMMENDATIONS FOR EXECUTIVEACTION -- AGENCY COMMENTS AND OUR EVALUATION -- List of Committees -- APPENDIX I.SCOPE AND METHODOLOGY -- APPENDIX II.DOE'S USE OF TECHNOLOGY READINESSLEVELS TO ASSESS THE MATURITY OF SPENTFUEL RECYCLING TECHNOLOGIES -- INDEX.

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Digitale Medien

Dynamic changes in ovarian c-kit and Steel expression during the estrous reproductive cycle (1993)

Motro, Benny ; Bernstein, Alan

New York, NY [u.a.] : Wiley-Blackwell

Developmental Dynamics 197 (1993), S. 69-79

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ISSN: 1058-8388

Schlagwort(e): c-kit ; Steel ; Tyrosine kinases ; Gonadotropins ; Ovary ; Life and Medical Sciences ; Cell & Developmental Biology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Medizin

Notizen: W and Steel mutant mice exhibit similar developmental defects in melanogenesis, haematopoiesis, and gametogenesis. Consistent with the cell autonomous and microenvironmental nature of W and Sl mutations, respectively, W encodes the c-kit receptor tyrosine kinase while Steel enclodes the Kit ligand. Both c-kit and Steel are expressed in various cells in which no corresponding mutant phenotype has yet been demonstrated. In the adult ovary, certain stromal-derived cells (theca and interstitial), as well as oocytes, express c-kit, while granulosa cells express Steel. We show here that the cessation of oocyte growth, at the transition of the follicle to the antral stage, is associated with the cessation of Steel expression in the cumulus granulosa cells in the vicinity of the oocyte. These observations suggest a role for the Kit signaling pathway in oocyte growth or in meiotic arrest. In addition, the cyclic secretion of luteinizing hormone immediately and dramatically results in elevated Steel expression in mural granulosa cells and decreased levels of c-kit transcripts in stromal-derived cells. This influence of the estrous reproductive cycle on c-kit/Steel expression suggests that the Kit signaling pathway, in addition to its previously described role in primordial germ cell development, is involved in follicular development in the adult female. © 1993 Wiley-Liss, Inc.

Zusätzliches Material: 6 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/aja.1001970107

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Digitale Medien

The program of friend cell erythroid differentiation: Early changes in Na+/K+ ATPase function (1978)

Mager, Dixie ; Bernstein, Alan

New York, N.Y. : Wiley-Blackwell

Journal of Supramolecular Structure 8 (1978), S. 431-438

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ISSN: 0091-7419

Schlagwort(e): Friend cells ; Na+/K+ ATPase ; K+ ion levels ; transport changes ; differentiation ; Life Sciences ; Molecular Cell Biology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie , Chemie und Pharmazie , Medizin

Notizen: Treatment of Friend erythroleukemia cells with several different chemical agents causes an early decrease in the 86Rb+ influx mediated by Na+/K+ adenosine triphosphatase (ATPase). These agents, which induced Friend cells to differentiate, include dimethylsulfoxide (DMSO), ouabain, hypoxanthine, and actinomycin D. The magnitude of the early decrease in 86Rb+ influx correlates with the proportion of cells in cultures of inducible Friend cell clones which later go on to synthesize hemoglobin. Compounds which do not incude differentiation in these cells, such as xanthine, exogenous hematin, and erythropoietin, do not cause a change in 86Rb+ influx. A change in the intracellular K+ ion concentration does not occur during induction by DMSO because, although there is a decrease in K+ content per cell soon after induction, there is a parallel decrease in cell volume. These results and previous observations from this laboratory are discussed in terms of the posible involvement of the Na+/K+ ATPase in Friend cell differentiation.

Zusätzliches Material: 5 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jss.400080405

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