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  • 1
    Electronic Resource
    Electronic Resource
    Effect of coronary hyperperfusion on regional myocardial function and oxygen consumption of stunned myocardium in pigs (1991)
    Springer
    Basic research in cardiology 86 (1991), S. 534-543 
    Details
    ISSN: 1435-1803
    Keywords: Greggphenomenon ; regionalfunction ; stunnedmyocardium ; myocardialoxygenconsumption ; reperfusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The “Gregg phenomenon” implies that myocardial function and oxygen consumption ( $$M\dot VO_2 $$ ) increase when coronary perfusion is enhanced within or above the autoregulatory range. We have recently demonstrated that the “Gregg phenomenon” has no significance for regional myocardial function and $$M\dot VO_2 $$ in anesthetized swine in situ. There is, however, some evidence that the “Gregg phenomenon” may exist within stunned myocardium. To test whether coronary hyperperfusion increases regional myocardial function and $$M\dot VO_2 $$ in stunned myocardium, in six anesthetized swine the left anterior descending coronary artery (LAD) was cannulated and perfused at constant pressure (CAP) using an extracorporal circuit. The coronary vein which parallels the LAD was cannulated to allow measurement of regional $$M\dot VO_2 $$ and regional systolic wall thickening (WT%) of the anterior myocardium was assessed using sonomicrometry. Blood flow (CBF) to the LAD was increased by increasing CAP within the extracorporal circuit or by intracoronary adenosine infusion (150 μg/min). In normal myocardium, increasing CBF from 71.4 ± 19.7 (SD) to 156.7 ± 48.8 ml/min/100 g by increasing CAP from 100 ± 10 to 190 ± 10 mm Hg or increasing CBF from 75.1 ± 29.1 to 189.2 ± 45.8 ml/min/100 g by intracoronary adenosine infusion did not increase WT% (34.3 ± 12.2 % vs 32.1 ± 10.6 % and 32.3 ± 10.7 % vs 30.1 ± 13.2 %, respectively). $$M\dot VO_2 $$ was not changed during enhanced CAP (6.94 ± 1.05 vs 8.10 ± 1.08 ml/min/100 g) and during intracoronary adenosine infusion (6.67 ± 1.45 vs 7.30 ± 2.23 ml/min/100 g). Twenty min of hypoperfusion followed by 30 min of reperfusion depressed WT% by 47 % (p 〈 0.05). However, $$M\dot VO_2 $$ was only decreased by 23 % (NS). In the stunned myocardium, increasing CBF from 62.1 ± 36.4 to 157.1 ± 60.0 ml/min by increasing CAP was not associated with an increase in WT%. $$M\dot VO_2 $$ , however, increased from 5.14 ± 1.07 to 8.88 ± 1.83 ml/min/100 g (p 〈 0.05). Comparable results were achieved when CBF was increased from 60.3 ± 28.7 to 176.9 ± 48.5 ml/min by intracoronary adenosine infusion. WT% was unaffected, while $$M\dot VO_2 $$ increased from 4.69 ± 0.92 to 9.46 ± 3.39 ml/min/100 g (p 〈 0.05). Thus, increasing coronary perfusion within or above the autoregulatory range increases $$M\dot VO_2 $$ in stunned myocardium, but without a simultaneous increase in regional myocardial function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02190703
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  • 2
    Electronic Resource
    Electronic Resource
    Stunned myocardium: inotropic reserve and pharmacological attenuation (1995)
    Springer
    Basic research in cardiology 90 (1995), S. 294-296 
    Details
    ISSN: 1435-1803
    Keywords: Myocardial ischemia ; reperfusion ; inotropic reserve calcium antagonists ; ACE inhibitors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00797904
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  • 3
    Electronic Resource
    Electronic Resource
    Ischemic preconditioning and myocardial hibernation: Is there a common mechanism? (1996)
    Springer
    Basic research in cardiology 91 (1996), S. 50-52 
    Details
    ISSN: 1435-1803
    Keywords: Myocardial ischemia ; reperfusion ; myocarial infarction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: In conclusion 1)Despite certain similarities between ischemic preconditioning and myocardial hibernation, these two cardioprotective phenomena are different in nature. 2) Intermittent reperfusion inbetween the preconditioning and the sustained ischemic period is not necessary for infarct size reduction by ischemic preconditioning.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00788864
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  • 4
    Electronic Resource
    Electronic Resource
    Über den mit Säuren katalysierten Abbau von Poly-3,4-acrolein (1966)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 78 (1966), S. 613-613 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19660781156
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  • 5
    Electronic Resource
    Electronic Resource
    Polymere mit atropisomeren Biphenyl-Grundbausteinen (1967)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 79 (1967), S. 422-422 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19670790936
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  • 6
    Electronic Resource
    Electronic Resource
    Synthetische makromolekulare Stoffe mit reaktiven Gruppen (1957)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 69 (1957), S. 153-171 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird über Synthese, Eigenschaften und Reaktionen einiger makromolekularer Stoffe mit reaktiven Gruppen berichtet, und zwar über Derivate der Polyacrylsäure (Polyacrylsäure-hydrazid, Polyacrylhydroxamsäure, Polyacrylsäureamid), des Polyvinylalkohols, über Polyacrolein und Polymethacrolein, Polyvinylsulfonsäure und ihre Derivate sowie über Copolymere aus Styrol und Maleinsäureanhydrid. An den reaktiven Gruppen dieser polymeren Stoffe werden chemische Reaktionen ausgeführt. Dabei zeigt sich, daß unter Bedingungen, die dem makromolekularen Bau des Reaktionspartners angepaßt sind, eine Reihe von Reaktionen, die aus der niedermolekularen Chemie gut bekannt sind, auf solche Polymere übertragen werden können. Dadurch werden neue makromolekulare Stoffe zugänglich, die durch Polymerisation oder Polykondensation nicht zu erhalten sind.
    Additional Material: 10 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19570690502
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  • 7
    Electronic Resource
    Electronic Resource
    Methoden und Probleme beim Studium optisch aktiver Polymerer (1966)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 78 (1966), S. 909-909 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19660781821
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  • 8
    Electronic Resource
    Electronic Resource
    Neuere Untersuchungen über optisch aktive Polymere (1967)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 79 (1967), S. 280-280 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19670790621
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  • 9
    Electronic Resource
    Electronic Resource
    1 3C-NMR-Spektroskopie an Polyäthern (1974)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 86 (1974), S. 450-450 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19740861216
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  • 10
    Electronic Resource
    Electronic Resource
    Methods and Problems in the Study of Optically Active Polymers (1966)
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 5 (1966), S. 850-850 
    Details
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/anie.196608501
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