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  • 1
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin / Heidelberg,
    Keywords: Climatology -- Mathematical models. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (66 pages)
    Edition: 1st ed.
    ISBN: 9783642364648
    Series Statement: SpringerBriefs in Earth System Sciences Series
    DDC: 550
    Language: English
    Note: Intro -- Earth System Modelling - Volume 4 -- Preface -- Contents -- Contributors -- 1 Input/Output and Postprocessing -- 2 Parallel I/O Basics -- 2.1 The I/O Software Stack -- 2.2 Parallel File Systems -- 2.3 MPI-IO -- 2.4 Data Format Libraries -- 2.5 Applying I/O Lessons to Applications -- 2.6 Parallel I/O Today and Tomorrow -- References -- 3 ESM I/O Layers -- 3.1 ESM I/O Layers: Design Considerations -- 3.2 An ESM Parallel I/O Class Library -- 3.2.1 mpp_io -- 3.2.2 Other ESM Parallel I/O Libraries -- 3.3 ESM Post-Processing Tools and Libraries -- 3.4 Discussion -- References -- 4 Data Storage -- 4.1 Hierarchical Storage Management: An Introduction -- 4.2 An Abstraction for HSMs: A Three-Level Storage Model -- 4.3 Discussion: HSM Strategies -- References -- 5 Data Representation -- 5.1 Scientific Data File Formats -- 5.1.1 NetCDF -- 5.1.2 HDF -- 5.1.3 GRIB -- 5.2 Remote Data Access -- 5.2.1 Bulk Access -- 5.2.2 Remote Subsetting in Index Space -- 5.2.3 Remote Subsetting in Coordinate Space -- 5.3 Georeferencing Coordinate Systems and Metadata -- 5.3.1 CF Conventions -- 5.3.2 Other Georeferencing Conventions -- 5.3.3 Discovery Versus Use Metadata -- 5.4 Data Models -- 5.4.1 ISO/OGC Models -- 5.5 Data Aggregation -- 5.6 Case Study: Attribution and Detection -- References -- 6 Data Analysis and Visualization -- 6.1 Background and History -- 6.2 The Analysis Process -- 6.3 Current Platforms Used for Data Analysis and Visualization -- 6.4 Community Tools and Environments -- 6.5 Use Case Example -- 6.6 Future Challenges and Directions -- 7 Future Perspectives -- References -- Glossary -- Index.
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  • 2
    ISSN: 1432-2277
    Keywords: Key words Tacrolimus ; Cyclosporin ; Haemolytic uraemic syndrome ; Renal transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Five patients with cyclosporin-related haemolytic uraemic syndrome (HUS) following cadaveric renal transplantation were converted from cyclosporin- to tacrolimus-based immunosuppression. All patients had biochemical, haematological and biopsy evidence of HUS at the time of conversion. Four of the patients showed complete resolution of the syndrome within 1 week of conversion with normalisation of haemoglobin, platelets and lactate dehydrogenase levels. In the fifth patient renal function stabilised with slow resolution of the haematological and biochemical parameters. Four of the five patients are still taking tacrolimus, one having converted back to cyclosporin due to marked hair loss. We conclude that conversion to tacrolimus appears to be an effective treatment for cyclosporin-related HUS following renal transplantation.
    Type of Medium: Electronic Resource
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