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  • Delia radicum  (1)
  • N-acetyl aspartate  (1)
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Keywords
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  • 1
    Electronic Resource
    Electronic Resource
    Metal composition as a natural marker in anthomyiid flyDelia radicum (L.) (1989)
    Springer
    Journal of chemical ecology 15 (1989), S. 1231-1239 
    Details
    ISSN: 1573-1561
    Keywords: Graphite furnace ; heavy metals ; chemoprints ; Delia radicum ; Diptera ; Anthomyiidae ; surface adsorption ; oxidation states ; metal cations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Graphite furnace and flame atomic absorption spectroscopy were used to make quantitative determinations of a range of metallic cation contents of wet-ashed female individuals ofDelia radicum (L.) from a laboratory culture reared under controlled conditions and freeze-dried upon emergence. Analyses were done for seven elements: Fe, Zn, Cu, Pb, AI, Mg, and K. The quantities of K and Mg present were positively related to the dry weight of individual flies, while the others showed an exponential decrease in concentration with increasing fly weight. This difference is attributed to the different roles of surface adsorption of metals with higher oxidation states and the high absorption efficiencies of those existing as oxidation states 1 and 2. The weight of the insect is therefore a major factor in determining the individual's chemoprint. The implications of this observation for other studies are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01014825
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Deoletion of brain glutathione is accompanied by impaired micochondrial function and decreased N-acetyl aspartate concentration (1995)
    Springer
    Neurochemical research 20 (1995), S. 31-38 
    Details
    ISSN: 1573-6903
    Keywords: Glutathione ; mitochondria ; N-acetyl aspartate ; oxidative stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of depletion of reduced glutathione (GSH) on brain mitochondrial function and N-acetyl aspartate concentration has been investigated. Using pre-weanling rats, GSH was depleted by L-buthionine sulfoximine administration for up to 10 days. In both whole brain homogenates and purified mitochondrial preparations complex IV (cytochrome c oxidase) activity was decreased, by up to 27%, as a result of this treatment. In addition, after 10 days of GSH depletion, citrate synthase activity was significantly reduced, by 18%, in the purified mitochondrial preparations, but not in whole brain homogenates, suggesting increased leakiness of the mitochondrial membrane. The whole brain N-acetyl aspartate concentration was also significantly depleted at this time point, by 11%. It is concluded that brain GSH is important for the maintenance of optimum mitochondrial function and that prolonged depletion leads also to loss of neuronal integrity. The relevance of these findings to Parkinson's disease and the inborn errors of glutathione mtabolism are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00995149
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    Paper (German National Licenses)
    Fulltext
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