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  • functional bowel disorders  (2)
  • motility  (2)
  • Constipation  (1)
Document type
Keywords
Publisher
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  • 1
    Electronic Resource
    Electronic Resource
    Abnormal rectosigmoid myoelectric response to eating in patients with severe idiopathic constipation (Slow-transit type) (1992)
    Springer
    Diseases of the colon & rectum 35 (1992), S. 753-756 
    Details
    ISSN: 1530-0358
    Keywords: Colon ; Constipation ; Eating ; Myoelectric
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pathophysiologic mechanisms responsible for severe chronic constipation are poorly understood. In particular, most of the published studies have lumped together patients having different subtypes of constipation, with different and often conflicting results. We studied six patients complaining of severe idiopathic constipation and displaying homogeneous clinical and pathophysiologic features (i.e.,patients with slow-transit type constipation) to evaluate their myoelectric spiking responses to food ingestion. Ten healthy subjects acted as controls. The constipated patients failed to show the increase in myoelectric spiking activity that was seen in controls immediately following the meals, suggesting the possibility of a neurogenic defect in this condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02050324
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    U. S. Householder survey of functional gastrointestinal disorders (1993)
    Springer
    Digestive diseases and sciences 38 (1993), S. 1569-1580 
    Details
    ISSN: 1573-2568
    Keywords: functional bowel disorders ; epidemiology ; diagnosis ; demography ; health care use ; work absenteeism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our objective was to obtain national data of the estimated prevalence, sociodemographic relationships, and health impact of persons with functional gastrointestinal disorders. We surveyed a stratified probability random sample of U.S householders selected from a data base of a national market firm (National Family Opinion, Inc.). Questions were asked about bowel symptoms, sociodemographic associations, work absenteeism, and physician visits. The sampling frame was constructed to be demographically similar to the U.S. householder population based on geographic region, age of householder, population density, household income and household size. Of 8250 mailings, 5430 were returned suitable for analysis (66% response). The survey assessed the prevalence of 20 functional gastrointestinal syndromes based on fulfillment of multinational diagnostic (Rome) criteria. Additional variables studied included: demographic status, work absenteeism, health care use, employment status, family income, geographic area of residence, population density, and number of persons in household. For this sample, 69% reported having at least one of 20 functional gastrointestinal syndromes in the previous three months. The symptoms were attributed to four major anatomic regions: esophageal (42%), gastroduodenal (26%), bowel (44%), and anorectal (26%), with considerable overlap. Females reported greater frequencies of globus, functional dysphagia, irritable bowel syndrome, functional constipation, functional abdominal pain, functional biliary pain and dyschezia; males reported greater frequencies of aerophagia and functional bloating. Symptom reporting, except for incontinence, declines with age, and low income is associated with greater symptom reporting. The rate of work/school absenteeism and physician visits is increased for those having a functional gastrointestinal disorder. Furthermore, the greatest rates are associated with those having gross fecal incontinence and certain more painful functional gastrointestinal disorders such as chronic abdominal pain, biliary pain, functional dyspepsia and IBS. Preliminary information on the prevalence, socio-demographic features and health impact is provided for persons who fulfill diagnostic criteria for functional gastrointestinal disorders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01303162
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Functional bowel disorders (1995)
    Springer
    Digestive diseases and sciences 40 (1995), S. 986-995 
    Details
    ISSN: 1573-2568
    Keywords: functional bowel disorders ; irritable bowel syndrome ; chronic abdominal pain ; functional constipation ; illness severity index ; functional colonic diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a multicenter study of patients with painful functional bowel disorders (FBD), we compared the demographic, health status, and diagnostic features of patients with FBD and developed a functional bowel disorder severity index (FBDSI) for research and clinical care. Two hundred seventy patients with FBD in the United States, England, and Canada were surveyed on symptoms and health status, and their physicians made a diagnosis and rated illness severity as mild, moderate, or severe. Comparisons of 22 demographic and clinical variables were made by study site in addition to physicians' severity ratings. To develop the FBDSI, multiple regression analysis used the demographic and clinical variables to predict the physician's rating of severity. We found that most health status measures of patients with FBD across study sites are comparable and the derived and validated FBDSI scoring system uses three easy to obtain variables: FBDSI = [current pain by visual analog scale (0–100)] + [diagnosis of chronic functional abdominal pain (0 if absent and 106 if present)] + [number of physicians visits over previous six months × 11]. The FBDSI can be used to select patients for research protocols and/or follow their clinical outcome or response to treatments over time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02064187
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Impaired colonic motor response to cholinergic stimulation in patients with severe chronic idiopathic (slow transit type) constipation (1993)
    Springer
    Digestive diseases and sciences 38 (1993), S. 1040-1045 
    Details
    ISSN: 1573-2568
    Keywords: cholinergic ; colon ; constipation ; edrophonium ; motility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chronic idiopathic constipation, especially the slow transit type, is a troubling problem often afficting young women. The pathophysiological basis for this entity is unknown, although a defective cholinergic innervation has been postulated. We tested the hypothesis that cholinergic colonic innervation is deranged in this condition by studying colonic motor activity after strong cholinergic stimulation with edrophonium chloride in 14 women complaining of slow transit constipation. Unlike healthy subjects, constipated patients showed minimal or no response to edrophonium injection. It is concluded that in slow transit constipation there is an important alteration of colonic cholinergic activity and that edrophonium chloride may represent a useful test drug for colonic pathophysiological investigations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01295719
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Pattern-recognition program for analysis of colon myoelectric and pressure data (1987)
    Springer
    Digestive diseases and sciences 32 (1987), S. 953-961 
    Details
    ISSN: 1573-2568
    Keywords: scoring ; motility ; myoelectric activity ; computer ; spectral analysis ; fast Fourier transform ; pattern recognition ; colon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A pattern-recognition program was developed which emulates visual scoring of colonic myoelectric and pressure recordings. It smoothes digitized data with a moving average filter, computes difference scores between successive groups of three data points, and uses the signs of these difference scores to detect the beginning and end of waves. Adjacent waves are merged if their means are closer than 1.67 times the sum of their standard deviations, and amplitude and duration criteria are used to exclude nonsignificant waves. When compared to four experienced human scorers on randomly selected records, the program agreed as well with the human scorers as they agreed with each other, and it approached the level of agreement of these observers with themselves when they were asked to rescore the same records blindly four to six weeks later. Human scorers agreed with themselves on 36–71% of myoelectric slow waves and on 42–88% of pressure waves, compared to 100% test-retest reliability for the pattern-recognition program. Frequency histograms of the duration of waves detected by the pattern-recognition program differed from the spectra generated by the fast Fourier transform (FFT) method. This pattern-recognition program provides an alternative to spectral analysis for the reliable and objective quantification of colonic myoelectric slow waves and pressure waves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297183
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    Paper (German National Licenses)
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