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  • irritable bowel syndrome  (4)
  • motility  (2)
  • Constipation  (1)
  • Motility  (1)
Document type
Keywords
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  • 1
    Electronic Resource
    Electronic Resource
    Intact colonic motor response to sudden awakening from sleep in patients with chronic idiopathic (slow-transit) constipation (1998)
    Springer
    Diseases of the colon & rectum 41 (1998), S. 1550-1555 
    Details
    ISSN: 1530-0358
    Keywords: Awakening ; Colon ; Motility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: There are few data about the relationships between colonic motor behavior and higher brain functions, such as sleep. Previous studies were done in healthy subjects, and it is unknown whether patients with functional motor disorders of the colon behave differently. This study was designed to characterize colonic motor activity in patients with constipation, both during sleep and after sudden awakening, and to compare it with that of healthy subjects. Our working hypothesis was that patients with constipation would have an impaired response to sudden awakening. PATIENTS AND METHODS: Twelve chronically constipated women, 22 to 49 years old, were recruited for the study, and their data were compared with those obtained from 12 healthy female volunteers, 21 to 38 years old. Manometric studies were performed in the descending and sigmoid colon for 30 minutes during sleep (immediately before awakening) and 30 minutes after being awakened suddenly. A motility index was calculated before and after the stimulus. RESULTS: In both groups motility in the descending and the sigmoid colon was almost absent during sleep and significantly increased after sudden awakening. No difference in postawakening values was found between patients with constipation and controls. CONCLUSIONS: In patients with chronic constipation, the brain-gut control of some fundamental mechanisms governing colonic motility is preserved. These data suggest that the alterations of colonic motility described in chronic constipation may be caused by an intrinsic dysfunction of the viscus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02237305
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  • 2
    Electronic Resource
    Electronic Resource
    Abnormal rectosigmoid myoelectric response to eating in patients with severe idiopathic constipation (Slow-transit type) (1992)
    Springer
    Diseases of the colon & rectum 35 (1992), S. 753-756 
    Details
    ISSN: 1530-0358
    Keywords: Colon ; Constipation ; Eating ; Myoelectric
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pathophysiologic mechanisms responsible for severe chronic constipation are poorly understood. In particular, most of the published studies have lumped together patients having different subtypes of constipation, with different and often conflicting results. We studied six patients complaining of severe idiopathic constipation and displaying homogeneous clinical and pathophysiologic features (i.e.,patients with slow-transit type constipation) to evaluate their myoelectric spiking responses to food ingestion. Ten healthy subjects acted as controls. The constipated patients failed to show the increase in myoelectric spiking activity that was seen in controls immediately following the meals, suggesting the possibility of a neurogenic defect in this condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02050324
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Functional bowel disorders (1995)
    Springer
    Digestive diseases and sciences 40 (1995), S. 986-995 
    Details
    ISSN: 1573-2568
    Keywords: functional bowel disorders ; irritable bowel syndrome ; chronic abdominal pain ; functional constipation ; illness severity index ; functional colonic diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a multicenter study of patients with painful functional bowel disorders (FBD), we compared the demographic, health status, and diagnostic features of patients with FBD and developed a functional bowel disorder severity index (FBDSI) for research and clinical care. Two hundred seventy patients with FBD in the United States, England, and Canada were surveyed on symptoms and health status, and their physicians made a diagnosis and rated illness severity as mild, moderate, or severe. Comparisons of 22 demographic and clinical variables were made by study site in addition to physicians' severity ratings. To develop the FBDSI, multiple regression analysis used the demographic and clinical variables to predict the physician's rating of severity. We found that most health status measures of patients with FBD across study sites are comparable and the derived and validated FBDSI scoring system uses three easy to obtain variables: FBDSI = [current pain by visual analog scale (0–100)] + [diagnosis of chronic functional abdominal pain (0 if absent and 106 if present)] + [number of physicians visits over previous six months × 11]. The FBDSI can be used to select patients for research protocols and/or follow their clinical outcome or response to treatments over time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02064187
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Impact of irritable bowel syndrome on quality of life (1996)
    Springer
    Digestive diseases and sciences 41 (1996), S. 2248-2253 
    Details
    ISSN: 1573-2568
    Keywords: quality of life ; irritable bowel syndrome ; neuroticism ; psychological distress ; outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aims of this study were to determine the impact of irritable bowel syndrome on quality of life using a well-standardized measure, the SF-36, and to determine whether apparent impairments may be due to neuroticism. Undergraduate students with irritable bowel syndrome who had consulted a physician (41 females, 42 males), students with irritable bowel who had not consulted a physician (91 females, 74 males), and asymptomatic controls (52 females, 70 males) completed questionnaires on quality of life, neuroticism, and psychological distress. Patients showed greater impairment in quality of life than nonconsulters, who in turn showed greater impairment than controls. Neuroticism and psychological distress were correlated with all quality-of-life measures. However, when neuroticism and psychological distress were statistically partialed out, irritable bowel syndrome still had a significant negative impact. The SF-36 may be a useful outcome measure in treatment studies, but investigators will need to correct for confounding influences of neuroticism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02071408
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  • 5
    Electronic Resource
    Electronic Resource
    Impaired colonic motor response to cholinergic stimulation in patients with severe chronic idiopathic (slow transit type) constipation (1993)
    Springer
    Digestive diseases and sciences 38 (1993), S. 1040-1045 
    Details
    ISSN: 1573-2568
    Keywords: cholinergic ; colon ; constipation ; edrophonium ; motility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chronic idiopathic constipation, especially the slow transit type, is a troubling problem often afficting young women. The pathophysiological basis for this entity is unknown, although a defective cholinergic innervation has been postulated. We tested the hypothesis that cholinergic colonic innervation is deranged in this condition by studying colonic motor activity after strong cholinergic stimulation with edrophonium chloride in 14 women complaining of slow transit constipation. Unlike healthy subjects, constipated patients showed minimal or no response to edrophonium injection. It is concluded that in slow transit constipation there is an important alteration of colonic cholinergic activity and that edrophonium chloride may represent a useful test drug for colonic pathophysiological investigations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01295719
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Irritable bowel syndrome defined by factor analysis gender and race comparisons (1995)
    Springer
    Digestive diseases and sciences 40 (1995), S. 2647-2655 
    Details
    ISSN: 1573-2568
    Keywords: irritable bowel syndrome ; Manning criteria ; Rome consensus criteria ; gas ; constipation ; symptom questionnaire ; factor analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To examine the applicability across subgroups of the Manning criteria commonly used to diagnose the irritable bowel syndrome, a 22-item symptom questionnaire was administered to male and female African-American and Caucasian adults (N=1344). Principal components factor analysis with varimax rotation was used to identify symptom clusters. Consistent with the findings of a previous factor analytic study, three of the six Manning symptoms (loose stools and more frequent bowel movements with onset of pain, pain relieved by defecation) formed a cluster corresponding to the irritable bowel syndrome in all subgroups. It is concluded that: (1) The three core Manning symptoms have equal applicability to both genders and to African-Americans as well as to Caucasians. They are useful symptom criteria for the diagnosis of IBS when used in conjunction with medical evaluation. (2) Three of the six Manning symptoms rarely correlate with the others; if confirmed in patient samples, this would indicate that these three symptoms are not useful for making a diagnosis of the irritable bowel syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02220455
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  • 7
    Electronic Resource
    Electronic Resource
    Biofeedback treatment of gastrointestinal disorders (1992)
    Springer
    Applied psychophysiology and biofeedback 17 (1992), S. 59-76 
    Details
    ISSN: 1573-3270
    Keywords: biofeedback ; gastrointestinal ; fecal incontinence ; constipation ; irritable bowel syndrome ; aerophagia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Biofeedback has had a greater impact on gastroenterology than on any other medical subspeciality. Biofeedback is the treatment of choice for many of the most common types of fecal incontinence, and preliminary studies suggest that it is likely to become a preferred method for treating patients with constipation related to inability to relax the striated pelvic floor muscles during defecation. This dysfunction may account for up to 50% of patients with chronic constipation. Thermal biofeedback forms part of a multicomponent behavioral treatment for irritable bowel syndrome that is reported to be effective, and other promising applications of biofeedback for gastrointestinal disorders are under investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01000091
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Pattern-recognition program for analysis of colon myoelectric and pressure data (1987)
    Springer
    Digestive diseases and sciences 32 (1987), S. 953-961 
    Details
    ISSN: 1573-2568
    Keywords: scoring ; motility ; myoelectric activity ; computer ; spectral analysis ; fast Fourier transform ; pattern recognition ; colon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A pattern-recognition program was developed which emulates visual scoring of colonic myoelectric and pressure recordings. It smoothes digitized data with a moving average filter, computes difference scores between successive groups of three data points, and uses the signs of these difference scores to detect the beginning and end of waves. Adjacent waves are merged if their means are closer than 1.67 times the sum of their standard deviations, and amplitude and duration criteria are used to exclude nonsignificant waves. When compared to four experienced human scorers on randomly selected records, the program agreed as well with the human scorers as they agreed with each other, and it approached the level of agreement of these observers with themselves when they were asked to rescore the same records blindly four to six weeks later. Human scorers agreed with themselves on 36–71% of myoelectric slow waves and on 42–88% of pressure waves, compared to 100% test-retest reliability for the pattern-recognition program. Frequency histograms of the duration of waves detected by the pattern-recognition program differed from the spectra generated by the fast Fourier transform (FFT) method. This pattern-recognition program provides an alternative to spectral analysis for the reliable and objective quantification of colonic myoelectric slow waves and pressure waves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297183
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    Paper (German National Licenses)
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