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  • motility  (2)
  • Constipation  (1)
  • Manning criteria  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Abnormal rectosigmoid myoelectric response to eating in patients with severe idiopathic constipation (Slow-transit type) (1992)
    Springer
    Diseases of the colon & rectum 35 (1992), S. 753-756 
    Details
    ISSN: 1530-0358
    Keywords: Colon ; Constipation ; Eating ; Myoelectric
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pathophysiologic mechanisms responsible for severe chronic constipation are poorly understood. In particular, most of the published studies have lumped together patients having different subtypes of constipation, with different and often conflicting results. We studied six patients complaining of severe idiopathic constipation and displaying homogeneous clinical and pathophysiologic features (i.e.,patients with slow-transit type constipation) to evaluate their myoelectric spiking responses to food ingestion. Ten healthy subjects acted as controls. The constipated patients failed to show the increase in myoelectric spiking activity that was seen in controls immediately following the meals, suggesting the possibility of a neurogenic defect in this condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02050324
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Impaired colonic motor response to cholinergic stimulation in patients with severe chronic idiopathic (slow transit type) constipation (1993)
    Springer
    Digestive diseases and sciences 38 (1993), S. 1040-1045 
    Details
    ISSN: 1573-2568
    Keywords: cholinergic ; colon ; constipation ; edrophonium ; motility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chronic idiopathic constipation, especially the slow transit type, is a troubling problem often afficting young women. The pathophysiological basis for this entity is unknown, although a defective cholinergic innervation has been postulated. We tested the hypothesis that cholinergic colonic innervation is deranged in this condition by studying colonic motor activity after strong cholinergic stimulation with edrophonium chloride in 14 women complaining of slow transit constipation. Unlike healthy subjects, constipated patients showed minimal or no response to edrophonium injection. It is concluded that in slow transit constipation there is an important alteration of colonic cholinergic activity and that edrophonium chloride may represent a useful test drug for colonic pathophysiological investigations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01295719
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Irritable bowel syndrome defined by factor analysis gender and race comparisons (1995)
    Springer
    Digestive diseases and sciences 40 (1995), S. 2647-2655 
    Details
    ISSN: 1573-2568
    Keywords: irritable bowel syndrome ; Manning criteria ; Rome consensus criteria ; gas ; constipation ; symptom questionnaire ; factor analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To examine the applicability across subgroups of the Manning criteria commonly used to diagnose the irritable bowel syndrome, a 22-item symptom questionnaire was administered to male and female African-American and Caucasian adults (N=1344). Principal components factor analysis with varimax rotation was used to identify symptom clusters. Consistent with the findings of a previous factor analytic study, three of the six Manning symptoms (loose stools and more frequent bowel movements with onset of pain, pain relieved by defecation) formed a cluster corresponding to the irritable bowel syndrome in all subgroups. It is concluded that: (1) The three core Manning symptoms have equal applicability to both genders and to African-Americans as well as to Caucasians. They are useful symptom criteria for the diagnosis of IBS when used in conjunction with medical evaluation. (2) Three of the six Manning symptoms rarely correlate with the others; if confirmed in patient samples, this would indicate that these three symptoms are not useful for making a diagnosis of the irritable bowel syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02220455
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Pattern-recognition program for analysis of colon myoelectric and pressure data (1987)
    Springer
    Digestive diseases and sciences 32 (1987), S. 953-961 
    Details
    ISSN: 1573-2568
    Keywords: scoring ; motility ; myoelectric activity ; computer ; spectral analysis ; fast Fourier transform ; pattern recognition ; colon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A pattern-recognition program was developed which emulates visual scoring of colonic myoelectric and pressure recordings. It smoothes digitized data with a moving average filter, computes difference scores between successive groups of three data points, and uses the signs of these difference scores to detect the beginning and end of waves. Adjacent waves are merged if their means are closer than 1.67 times the sum of their standard deviations, and amplitude and duration criteria are used to exclude nonsignificant waves. When compared to four experienced human scorers on randomly selected records, the program agreed as well with the human scorers as they agreed with each other, and it approached the level of agreement of these observers with themselves when they were asked to rescore the same records blindly four to six weeks later. Human scorers agreed with themselves on 36–71% of myoelectric slow waves and on 42–88% of pressure waves, compared to 100% test-retest reliability for the pattern-recognition program. Frequency histograms of the duration of waves detected by the pattern-recognition program differed from the spectra generated by the fast Fourier transform (FFT) method. This pattern-recognition program provides an alternative to spectral analysis for the reliable and objective quantification of colonic myoelectric slow waves and pressure waves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297183
    Location Call Number Limitation Availability
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    Paper (German National Licenses)
    Fulltext
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