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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 135 (1995), S. 105-121 
    ISSN: 0942-0940
    Keywords: Cervical spine ; cervical spondylosis ; cervical microsurgery ; cervical osteosynthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Surgical treatment of cervical myelopathy due to multi-segmental cervical spondylosis (MSCS) is currently performed by either anterior or posterior approaches. Considering the complex nature of the underlying disease involving more than one cervical segment, as well as the patho-biomechanical features of the spondylotic cervical spine, adequate decompression of the spinal cord and correction of hypermobility should be achieved by surgery in one stage, in order to achieve positive immediate and long-term benefit for the patient suffering from progressive myelopathy. Recently, anterior decompressive surgery, consisting of single or multi-level vertebrectomy, microsurgical epidural decompression and osteosynthesis has emerged as an aggressive therapeutic approach for the treatment of MSCS. Based on the experience of a series of 92 patients with progressive cervical myelopathy due to MSCS operated on using the above described combined techniques, as well as the results from a limited number of clinical studies of anterior decompressive surgery in MSCS patients from the literature, the pathophysiological considerations, surgical indications, surgical technique as well as clinical results and complications of anterior surgery in patients with MSCS are reviewed and discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Cervical spine ; microsurgery ; elderly patients ; spinal tumour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In this retrospective study, the results of surgery were examined in 25 patients, 65 years of age or older, suffering from malignant tumour growth along the cervical spine. The group consisted of 17 men and 8 women. The mean age was 73 years, ranging from 66 to 88 years. The pathology identified was metastasis in 23 patients, and plasmocytoma in two. The tumour localization involved a single segment of the cervical spine in 12 patients, two segments in 8 patients, three segments in 4 patients, and four segments in one patient. Pre-operatively, 8 patients (32%) suffered solely from severe pain. 6 patients (24%) showed severe pain and radicular nerve compression. 5 patients (20%) had incomplete para- or tetraparesis but were able to walk, and again 6 patients (24%) had incomplete para- or tetraparesis, and were unable to walk. A multitude of accompanying systemic diseases was present in the majority of patients. Evaluation of the peri-operative risk profile was performed using the American Society of Anaesthesiology (ASA) Grading of Physical Status Score. Operation consisted of microsurgical tumour removal, usually incorporating a single- or multi-level vertebrectomy, with radical epidural decompression, and grafting with bone cement followed by an appropriate osteosynthesis. Of the whole cohort of patients treated, four patients were still alive at the time of the last follow-up evaluation. 21 patients died. Four patients died within seven days after surgery. The remaining 17 patients died during the follow-up period. All of these patients died from systemic spread of their primary cancer. The results of surgery in terms of postoperative neurological outcome were as follows: 11 patients or 44% were improved by surgery. 7 patients (28%) were unchanged, three patients (12%) became worse, and four patients (16%) died. With regard to functional outcome, 73% of the patients with severe pre-operative neurological deficits showed significant postoperative amelioration of symptoms. 19 patients became ambulatory until the final stage of their disease. It is concluded, that according to the results of this limited study, a general nihilistic or purely conservative approach for the treatment of elderly patients suffering from secondary malignancy of the cervical spine is not justified. With proper patient selection, aggressive surgery leads to significant amelioration of pre-operatively existing neurological deficits and long-term ambulation in a considerable percentage of the patients.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0942-0940
    Keywords: Cervical spine ; tumour ; trauma ; infection ; operative treatment ; spondylectomy ; microsurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 44 patients with complex degenerative, traumatic, neoplastic and infectious disorders of the cervical spine an aggressive surgical approach was used, consisting of Spondylectomy, radical microsurgical decompression and osteosynthesis. The patient group consisted of 23 patients with multisegmental cervical spondylosis, 9 patients with primary or metastatic malignant tumour disease spread along the cervical spine, 6 patients with complex cervical trauma and 6 patients with infection affecting one or more cervical segments. Considering the heterogenity of the group of patients treated, a multitude of neurological symptoms and signs were present. Excruciating pain was the predominant symptom in 84% of the patients, followed by sensory and motor signs of varying degrees in 77% and 65% respectively. Involvement of the long tracts was present in 51%, gait disturbance in 49% and bladder disfunction in 28%. Considering the nature of the underlying disease, in the group with multisegmental cervical spondylosis (MSCS), advanced cervical myelopathy was the predominant clinical symptom, whereas in those patients with trauma, tumour or infection, pain was the leading symptom, followed by disturbed motor and/or sensory function. Altogether 59 vertebrae have been removed in the 44 patients. In 28 patients spondylectomy was performed at one level, in 15 patients at two levels and in one female tumour patient at three levels. In 34 patients an iliac crest bone graft was used and in 10 patients bone cement. Within the observation period, solid fusion was achieved in all patients. In one tumour patient screw loosening was demonstrable at follow-up, but the fusion remained stable. 2 patients with infectious disease required re-operation due to significant loosening of screws and plates. However, after re-stabilization solid fusion was achieved. Considering amelioration of specific pre-operative symptoms and signs, excruciating pain responded best to the stabilizing procedure, with improvement in over 90% of the patients, followed by improvement of sensory and motor deficits in 85% and 82% respectively. Improvement in pre-operative gait disturbance could be achieved in 81% of the patients, while disturbance of bladder function is less likely to improve after surgery with a positive response in only 58%. None of the patients became neurologically worse after surgery. With regard to the underlying disease, patients with MSCS and tumour had the best results with overall improvement in 62% and 75% respectively. While in patients with infection improvement could be achieved in 58%, improvement in trauma patients was demonstrable in only 34% while in 66% the pre-operative clinical status remained unchanged. The surgical technique is described in detail, the results and four illustrative cases representing the therapeutic spectrum of this technique are presented. The necessity of strict adherence to microsurgical techniques for decompressive epidural surgery is especially stressed, as this is considered, apart from adequate osteosynthetic technique, to be the most important surgical factor determining the postoperative result in this challenging group of patients.
    Type of Medium: Electronic Resource
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