Publication Date:
2012-07-05
Description:
miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling The EMBO Journal 31, 2908 (2012). doi:10.1038/emboj.2012.130 Authors: Kristin Franke, Wolfgang Otto, Sascha Johannes, Jan Baumgart, Robert Nitsch & Stefan Schumacher The small GTPase RhoG plays a central role in actin remodelling during diverse biological processes such as neurite outgrowth, cell migration, phagocytosis of apoptotic cells, and the invasion of pathogenic bacteria. Although it is known that RhoG stimulates neurite outgrowth in the rat pheochromocytoma PC12
Keywords:
Cdc42ELMO–Dock180–Rac1 signallingmiR-124neuronal process complexityRhoG
Print ISSN:
0261-4189
Electronic ISSN:
1460-2075
Topics:
Biology
,
Medicine
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