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  • 1
    ISSN: 1573-1561
    Keywords: Attractants ; kairomone ; Caribbean fruit fly ; Anastrepha suspensa ; host fruit ; Diptera ; Tephritidae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Extracts of 22 fruits were tested for their attractancy toAnastrepha suspensa (Loew), the Caribbean fruit fly. Box-orange, calamondin, carambola, cattley guava, loquat, and Surinam-cherry were about equal in attractiveness to males and females. Nine synthetic chemicals, including four found in box-orange ripe seed, were attractive to females. Five synthetic chemicals, including two in box-orange ripe seed, were attractive to males. Farnesol,α-phellandrene, and 3-carene were highest in attractiveness to both males and females. Females were more attracted than males to 12 synthetic chemicals. These data suggest that host chemicals serve as attractants and that female and male specific attractants and traps could be developed from host kairomone data. These data also suggest that the volatilization of chemicals from water may play an important role in kairomone biology.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0878
    Keywords: Key words Voltage-gated Na+ channels ; Dunning cells ; Prostate cancer ; Morphology ; Tetrodotoxin ; Rat (Copenhagen)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Voltage-gated Na+ channels are expressed by highly metastatic MAT-LyLu cells, but not by poorly metastatic AT-2 cells, derived from the rodent Dunning model of prostatic cancer. We have investigated the possible involvement of these channels in the morphological development of the cells. Incubation of both the MAT-LyLu and the AT-2 cell line for 24 h with the Na+ channel blocker tetrodotoxin (TTX) at 6 μM altered the morphology only of the MAT-LyLu cell line. TTX produced significant decreases in: (a) cell process length and (b) field diameter, and increases in (c) cell body diameter and (d) process thickness. Importantly, 6 μM TTX had no significant effects on proliferation rates or cellular toxicity. The results suggest that Na+ channel activity plays a significant role in determining the morphological development of MAT-LyLu cells in such a way as to enhance their metastatic potential.
    Type of Medium: Electronic Resource
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