ISSN:
1432-072X
Keywords:
Enterococcus faecalis
;
Chemostat culture
;
Pyruvate dehydrogenase
;
NADH/NAD
;
Redox potential
;
Fructose-1,6-bisphosphate
;
Carbon metabolism
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Enterococcus faecalis NCTC 775 was grown anaerobically in chemostat culture with pyruvate as the energy source. At low culture pH values, high in vivo and in vitro activities were found for both pyruvate dehydrogenase and lactate dehydrogenase. At high culture pH values the carbon flux was shifted towards pyruvate formate lyase. Some mechanisms possibly involved in this metabolic switch are discussed. In particular attention is paid to the NADH/NAD ratio (redox potential) and the fructose-1,6-bisphosphate-dependent lactate dehydrogenase activity as possible regulatory factors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00249177
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