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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 1 (1983), S. 236-243 
    ISSN: 0736-0266
    Keywords: Blood flow ; Scanning agents ; Bone remodeling ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In mature dogs with comparable levels of bone remodeling, we produced either increased (with adenosine triphosphate) or decreased (with epinephrine) blood flow to one hindlimb. In 13 dogs (five control, four with increased flow, and four with decreased flow), we compared uptake, at 3 h after injection of radiolabeled diphosphonate in the mid-tibia, with blood flow as determined by microspheres. Blood flow was determined with 85Sr-labeled microspheres, and determination of uptake of 99mTc methylene diphosphonate (99mTc-MDP) was by a gamma detector. There was a linear relationship between changes in diphosphonate uptake and changes in blood flow at decreased and normal flows; however, at high flows the relationship was nonproportional, indicating a disproportionately slower increase in 99mTc-MDP uptake with increasing blood flow. In six dogs an initial 1-h uptake curve of 99mTc-MDP was determined in both control and experimental limbs under states of increased and decreased blood flow. The 30-min uptake value, 60-min uptake value, area under the curve, and the slope of the curve were related to flow as determined by microspheres. The data are consistent with the hypothesis that deposition of bone-concentrating isotopes such as 99mTc-MDP is partly controlled by blood flow; at subnormal and normal flows tracer uptake is closely related to blood flow, but at supranormal flow rates it is not and appears to be diffusion limited.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2022-06-17
    Description: Author Posting. © American Meteorological Society, 2022. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Physical Oceanography 52(3), (2022): 363–382, https://doi.org/10.1175/jpo-d-21-0084.1.
    Description: Meltwater from Greenland is an important freshwater source for the North Atlantic Ocean, released into the ocean at the head of fjords in the form of runoff, submarine melt, and icebergs. The meltwater release gives rise to complex in-fjord transformations that result in its dilution through mixing with other water masses. The transformed waters, which contain the meltwater, are exported from the fjords as a new water mass Glacially Modified Water (GMW). Here we use summer hydrographic data collected from 2013 to 2019 in Upernavik, a major glacial fjord in northwest Greenland, to describe the water masses that flow into the fjord from the shelf and the exported GMWs. Using an optimum multi-parameter technique across multiple years we then show that GMW is composed of 57.8% ± 8.1% Atlantic Water (AW), 41.0% ± 8.3% Polar Water (PW), 1.0% ± 0.1% subglacial discharge, and 0.2% ± 0.2% submarine meltwater. We show that the GMW fractional composition cannot be described by buoyant plume theory alone since it includes lateral mixing within the upper layers of the fjord not accounted for by buoyant plume dynamics. Consistent with its composition, we find that changes in GMW properties reflect changes in the AW and PW source waters. Using the obtained dilution ratios, this study suggests that the exchange across the fjord mouth during summer is on the order of 50 mSv (1 Sv ≡ 106 m3 s−1) (compared to a freshwater input of 0.5 mSv). This study provides a first-order parameterization for the exchange at the mouth of glacial fjords for large-scale ocean models.
    Description: This work was partially supported by the Centre for Climate Dynamics (SKD) at the Bjerknes Centre for Climate Research. The authors thank NASA and the OMG consortium for making observational data freely available, and acknowledge M. Morlighem for good support in the early stages of this project. MM and LHS and would also like to thank Ø. Paasche, the ACER project, and the U.S. Norway Fulbright Foundation for the Norwegian Arctic Chair Grant 2019–20 that made the visit to Scripps Institution of Oceanography possible. FS acknowledges support from the DOE Office of Science Grant DE-SC0020073, Heising-Simons Foundation and from NSF and OCE-1756272. DAS acknowledges support from U.K. NERC Grants NE/P011365/1, NE/T011920/1, and NERC Independent Research Fellowship NE/T011920/1. MW was supported by an appointment to the NASA Postdoctoral Program at the Jet Propulsion Laboratory, California Institute of Technology, administered by the Universities Space Research Association under contract with NASA. CSA would like to acknowledge Geocenter Denmark for support to the project “Upernavik Glacier.”
    Keywords: Ocean ; Arctic ; Atlantic Ocean ; Glaciers ; Ice sheets ; Buoyancy ; Entrainment ; In situ oceanic observations ; Annual variations
    Repository Name: Woods Hole Open Access Server
    Type: Article
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