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  • Sperm cell  (5)
  • Biochemistry and Biotechnology  (1)
  • Data mining -- Congresses.  (1)
  • EGF receptor  (1)
  • 1
    Online-Ressource
    Online-Ressource
    Berlin, Heidelberg :Springer Berlin / Heidelberg,
    Schlagwort(e): Data mining -- Congresses. ; Electronic books.
    Materialart: Online-Ressource
    Seiten: 1 online resource (540 pages)
    Ausgabe: 1st ed.
    ISBN: 9783642319006
    Serie: Lecture Notes in Computer Science Series ; v.7414
    DDC: 006.3
    Sprache: Englisch
    Anmerkung: Title -- Preface -- Organization -- Table of Contents -- Part I: Rough Sets and Its Generalizations -- A Characterization of Rough Separability -- Introduction -- Rough Sets and Indiscernibility Relations -- Rough Separability and Pseudometric Spaces -- Pseudometrics Determined by Families of Sets -- Equivalence of Pseudometric Spaces -- Conclusions -- References -- Data-Driven Valued Tolerance Relation -- Introduction -- Valued Tolerance Relation -- Data-Driven Valued Tolerance Relation -- Calculation of Tolerance Degree -- Auto-selection of Threshold -- Experiment Results -- Conclusions -- References -- Optimistic Multi-Granulation Fuzzy Rough Set Model Based on Triangular Norm -- Introduction -- The Rough Set Based on Triangular Norm -- Optimistic Multi-Granulation Fuzzy Rough Set Based on Triangular Norm -- Conclusions -- References -- Rough Set Model Based on Hybrid Tolerance Relation -- Introduction -- Preliminaries -- Strong and Weak Indiscernibility Relations -- Incomplete Information System and Tolerance Relations -- Weak Tolerance Relations -- Hybrid Tolerance Relation and Decision Rule -- Hybrid Tolerance Relation -- Decision Rule -- Conclusions -- References -- Scalable Improved Quick Reduct: Sample Based -- Introduction -- Overview of IQRA and IQRA_IG Algorithms -- Proposed SGIQRA_IG Algorithm -- Experiments and Results -- Analysis of Results -- Conclusion -- References -- Soft Rough Sets Based on Similarity Measures -- Introduction -- Preliminaries -- Analysis of Soft Rough Approximations -- Soft Fuzzy Rough Sets Based on Similarity Measures -- Concluding Remarks -- References -- Theory of Truth Degrees in Three Valued Formed System RSL -- Introduction -- Basic of Rough Set and Formed System RSL -- The Theory of Truth Degree -- Similarity Degree and a Pseudo-metric among Formulas -- Conclusion -- References. , Upper Approximation Reduction Based on Intuitionistic Fuzzy T Equivalence Information Systems -- Introduction -- Intuitionistic Fuzzy Rough Sets and Intuitionistic Fuzzy T Equivalence Information Systems -- Upper Approximation Reduction in IF T Equivalence Information Systems with Decision -- An Illustrated Example -- Conclusions -- References -- Part II: Rough Sets in Data and Knowledge Processing -- A Fuzzy-Rough Sets Based Compact Rule Induction Method for Classifying Hybrid Data -- Introduction -- Preliminary Notion of Rough Sets Based Rule Induction Method -- Fuzzy Rough Sets Based Compact Rule Learner -- Experiments and Discussion -- Conclusion -- References -- A New Intuitionistic Fuzzy Rough Set Approach for Decision Support -- Introduction -- Preliminaries -- Dominance-Based Rough Set Approach -- Intuitionistic Fuzzy Theory -- Uncertain Rule Induction -- Believe Factor -- Measurements -- Believable Rule Induction -- Illustrative Example -- Decision Table and Rough Approximations -- Believable Rule Induction -- Verification of Sorting Capability -- Conclusion -- References -- A New Rule Induction Method from a Decision Table Using a Statistical Test -- Introduction -- Model of Data Generation -- Proposal of Rule Estimation Method by Statistical Test -- Algorithm for Rule Induction -- Experimental Studies -- Conclusions -- References -- A Rough Neurocomputing Approach for Illumination Invariant Face Recognition System -- Introduction -- Rough Set Theory (RST) -- Proposed RNRS Architecture -- Design of ADNN -- Approximation Neuron -- Decider Neuron -- Architecture of ADNN -- Experimental Results -- Conclusion -- References -- An Approximation Decision Entropy Based Decision Tree Algorithm and Its Application in Intrusion Detection -- Introduction -- Preliminaries -- Approximation Decision Entropy -- Decision Tree Algorithm DTADE. , Experimental Results -- Conclusion -- References -- Application of Rough Set Theory to Prediction of Antimicrobial Activity of Bis-quaternary Ammonium Chlorides -- Introduction -- Material and Methods -- Material -- Discovery of Decision Rules Using DRSA -- Attribute Relevance -- Results and Discussion -- References -- Classification and Decision Based on Parallel Reducts and F-Rough Sets -- Introduction -- F-Rough Sets and Parallel Reducts -- Three Types of Classification(Decision) Based on Parallel Reducts and F-Rough Sets -- Specific Decision Subsystem -- Decision Subsystem Selected Randomly -- Deciding by a Majority Vote -- Conclusion -- References -- Evidential Clustering or Rough Clustering: The Choice Is Yours -- Introduction -- Similarities between ECM and RKM -- Strengths of ECM -- Strengths of RKM -- Conclusion -- References -- Heuristic for Attribute Selection Using Belief Discernibility Matrix -- Introduction -- Rough Set Theory -- Belief Function Theory -- Heuristic for Attribute Selection Method Using Belief Discernibility Matrix -- Uncertain Decision Table -- Feature Selection with Johnson´s Heuristic Algorithm -- Belief Discernibility Matrix -- Belief Rough Set Classifier -- Experimental Results -- Conclusion and Future Work -- References -- Incremental Rules Induction Based on Rule Layers -- Introduction -- Rough Sets and Probabilistic Rules -- Rough Set Theory -- Probabilistic Rules -- Problems in Incremental Rule Induction -- Theory for Incremental Learning -- Both: Negative -- R: Positive -- d: Positive -- d: Positive -- Updates of Accuracy and Coverage -- An Algorithm for Incremental Learning -- Algorithm -- Experimental Results -- Conclusion -- References -- Optimization of Inhibitory Decision Rules Relative to Length and Coverage -- Introduction -- Nonredundant Decision Rules -- Directed Acyclic Graph (T). , Procedures of Optimization Relative to Length and Coverage -- Experimental Results -- Conclusions -- References -- Parallelized Computing of Attribute Core Based on Rough Set Theory and MapReduce -- Introduction -- Parallel Algorithm for Computing Attribute Core Based on Rough Set and MapReduce -- Experiments and Discussion -- Case Study -- Comparative Experiments for Efficiency of the Proposed Algorithm -- Conclusion -- References -- Semi-supervised Vehicle Recognition: An Approximate Region Constrained Approach -- Introduction -- Semi-supervised Learning Based on Approximate Region Constraints (SsL-ARC) -- SsL-ARC Algorithm Framework -- Approximate Region Constraints -- Experiments -- Conclusions -- References -- Part III: Knowledge Technology -- A Color Image Segmentation Algorithm by Integrating Watershed with Region Merging -- Introduction -- Watershed Algorithm -- Merger of the Image Regions -- Distance Metric between Graph Regions -- Merger Algorithm of the Image Regions -- Experimental Results and Analysis -- Conclusion -- References -- A Mixed Strategy Multi-Objective Coevolutionary Algorithm Based on Single-Point Mutation and Particle Swarm Optimization -- Introduction -- Multi-Objective Optimization Problems -- Multi-Objective Coordination Operator Evolutionary Programming Based on Single Point and PSO Operator -- Mixed Strategy -- Maintenance of External Archive -- Algorithm Description -- The Experimental Results -- Experiment Setting -- Results and Analysis -- Summary -- References -- A Novel Distributed Machine Learning Method for Classification: Parallel Covering Algorithm -- Introduction -- Covering Algorithm Overview -- Learn Procedure -- Classification -- Parallel Covering Algorithm -- Experiments and Analysis -- Uniprocessor Environment -- Multi-core Parallel Computing Environment -- Conclusion -- References. , A Spatial Clustering Method for Points-with-Directions -- Introduction -- Related Work -- Points-with-Directions Clustering -- Problem Definition -- Spatial Clustering Method for Points-with-Directions -- The Limitations of PDC -- PDC+ -- Experimental Evaluation -- Conclusions and Future Work -- References -- An Argumentation Framework for Non-monotonic Reasoning in Description Logic -- Introduction -- The Description Logic ALC -- Defeasible ALC -- Inductive Terminologies -- Conclusion and Future Work -- References -- Analysis of Symmetry Properties for Bayesian Confirmation Measures -- Introduction -- Preliminaries -- Property of Bayesian Confirmation -- Properties of Symmetry -- A New Set of Symmetry Properties -- Conclusions -- References -- Applying Verbal Decision Analysis in Selecting Specific Practices of CMMI -- Introduction -- Verbal Decision Analysis: Overview and Application -- Conclusions, Future Works and Acknowledgment -- References -- Belief Networks in Classification of Laryngopathies Based on Speech Spectrum Analysis -- Introduction -- Laryngopathy Data -- Theoretical Foundations of BeliefSEEKER -- Experiments -- Conclusions -- References -- Comparing Similarity of Concepts Identified by Temporal Patterns of Terms in Biomedical Research Documents -- Introduction -- A Method for Analyzing Distances on Taxonomy and Temporal Patterns of Term Usage -- Obtaining Temporal Patterns of Data-Driven Indexes Related to Term Usages -- Defining Similarity of Terms on a Structured Taxonomy -- Analyzing Similarity of Terms in Temporal Patterns of Medical Research Documents -- Analysis of Disease over Time -- Obtaining Temporal Patterns of Medical Terms about Migraine Drug Therapy Studies -- Similarity of the Terms in Obtained Temporal Patterns on MeSH -- Conclusion -- References. , Extracting Incidental and Global Knowledge through Compact Pattern Trees in Distributed Environment.
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Sexual plant reproduction 7 (1994), S. 313-323 
    ISSN: 1432-2145
    Schlagwort(e): Cytoplasmic inheritance Double fertilization ; Embryo sac Mitochondrial transmission ; Tobacco ; Sperm cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Serially sectioned embryo sacs of Nicotiana tabacum were examined during fertilization events using transmission electron microscopy. After pollen tube discharge, the outer membrane of the sperm pair is removed, the two sperm cells are deposited in the degenerate synergid and the sperm cells migrate to the chalazal edge of the synergid where gametic fusion occurs. During fertilization, the male cytoplasm, including heritable organelles, is transmitted into the female reproductive cells as shown by: (1) the cytoplasmic confluence of one sperm and the central cell during cellular fusion, (2) the occurrence of sperm mitochondria (distinguished by ultrastructural differences) in the zygote cytoplasm and adjacent to the sperm nucleus, (3) the presence of darkly stained aggregates which are found exclusively in mature sperm cells within the cytoplasm of both female cells soon after cell fusion, and (4) the absence of any large enucleated cytoplasmic bodies containing recognizable organelles outside the zygote or endosperm cells. The infrequent occurrence of plastids in the sperm and the transmission of sperm cytoplasm into the egg during double fertilization provide the cytological basis for occasional biparental plastid inheritance as reported previously in tobacco. Although sperm mitochondria are transmitted into the egg/zygote, their inheritance has not been detected genetically. In one abnormal embryo sac, a pair of sperm cells was released into the cytoplasm of the presumptive zygote. Although pollen tube discharge usually removes the inner pollen-tube plasma membrane containing the two sperm cells, this did not occur in this case. When sperm cells are deposited in a degenerating synergid or outside of a cell, this outer membrane is removed, as it apparently is for fertilization.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Sexual plant reproduction 7 (1994), S. 324-332 
    ISSN: 1432-2145
    Schlagwort(e): Generative cell ; Male germ unit Nicotiana tabacum ; Pollen tube ; Sperm cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Generative and sperm cells were examined at four stages of development from generative cell formation to sperm cell maturation using serial transmission electron microscopy. The generative cell and vegetative nucleus are associated in a male germ unit association during pollen maturation and tube elongation, except for generative cell mitosis. At late stages of prophase, this association loosens; the generative cell separates from the vegetative nucleus at metaphase. Slender, unbranched, or occasionally branched projections may be found at one or both ends of the generative cell, or they may be single, blunt, and short. Slender projections are rare during anaphase and telophase. The vegetative nucleus moves back into apposition with one sperm cell at the end of mitosis. During the re-establishment of the association, the vegetative nucleus first touches the end of the leading sperm cell and then moves next to the middle of the sperm nucleus. As the sperm cells enter interphase, a conventional association is re-established between one cell and the vegetative nucleus through one or more long and slender cytoplasmic extensions; these associations are maintained throughout later passage in the pollen tube. During maturation, a significant increase occurs in the surface area of the sperm cells (particularly in the sperm cell in association with the vegetative nucleus), and a lesser increase in nuclear volume and surface area. Other sperm cell parameters, including those of heritable organelles, remain unchanged during sperm cell maturation.
    Materialart: Digitale Medien
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  • 4
    ISSN: 1432-2048
    Schlagwort(e): Autophagy ; Cytoplasmic inheritance ; Generative cell ; Nicotiana (reproductive cells) ; Plastid diminution ; Sperm cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The dynamics of plastid and mitochondrial populations in male reproductive cells of tobacco (Nicotiana tabacum L.) were examined during development using serial ultrathin sections and transmission electron microscopy to reconstruct 58 generative cells and 31 sperm cells at selected stages of maturation from generative cell formation through gametic fusion. The first haploid mitosis resulted in incomplete exclusion of plastids providing an average of 2.81 plastids and 82.7 mitochondria for each newly formed generative cell. During generative-cell maturation, plastid content decreased to an average of 0.48 plastids/generative cell at anthesis owing to autophagy of organelles. Plastids were present in low frequency within generative and sperm cells in the pollen tube and appeared to be transmitted, according to observations immediately prior to fertilization. This forms a cytological basis for genetic reports of occasional biparental plastid inheritance. In contrast, mitochondria were transmitted in larger numbers, and approximately 80 mitochondria per generative cell or sperm cell pair were retained throughout development. This provides a potentially stable source for the transmission of male mitochondrial DNA, if present at fertilization.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Protoplasma 152 (1989), S. 29-36 
    ISSN: 1615-6102
    Schlagwort(e): Male germ unit ; Nicotiana tabacum ; Pollen tube ; Sperm cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The structure of sperm cells and their association with the vegetative nucleus in pollen tubes ofNicotiana tabacum grown in styles were observed with the electron microscope, demonstrating the existence of a male germ unit. The two sperm cells are arranged in tandem and are closely associated with the vegetative nucleus, which always takes the lead. The leading sperm cell (SC 1) has a long and narrow cytoplasmic projection which lies within the enclaves of the much lobed vegetative nucleus, thus forming a physical association. The trailing sperm cell (SC 2) and the SC 1 are not only joined by a common transverse cell wall but also are surrounded by a periplasm bounded by the plasma membrane of the sperm cells and that of the vegetative cell, thus forming a structural connection. The sperm cells are elongated, with cytoplasmic projections at the anterior end of the SC 1 and at both ends of the SC 2. The cytoplasm of both sperm cells includes mitochondria, endoplasmic reticulum, dictyosomes, ribosomes, small vacuoles and axially oriented microtubules. No plastids were observed.
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Protoplasma 147 (1988), S. 55-63 
    ISSN: 1615-6102
    Schlagwort(e): Generative cell ; Sperm cell ; Treetomato ; Ultrastructure ; Vegetative nucleus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The structure of the generative cell and its association with the vegetative nucleus in the pollen tube ofCyphomandra betacea Sendt. were observed with the electron microscope. The generative cell, bounded by its own plasma membrane and the inner plasma membrane of the vegetative cell, possesses the cytoplasmic extension which lies within the embayments of a vegetative nucleus. The generative cell contains the normal complement of organelles and, especially, microtubules which cluster into several groups adjacent to the plasma membrane, oriented along the longitudinal axis of the cell. In the pollen tube reaching the lower end of the style aftersemivivo pollination, both of the sperm cells are elongated and polyribosomes and microtubules are the outstanding feature in the cytoplasm. The two sperm cells are connected by a common transverse cell wall, while cytoplasmic channels exist in both the periplasm of the two sperm cells and the transverse wall. The leading sperm cell (Svn) is closely associated with the vegetative nucleus. Thus the present study demonstrates the existence of the male germ unit in the pollen tube ofC. betacea. The possible cytoplasmic continuity between the sperm cells and between the gametes and vegetative cell is considered.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    ISSN: 1573-7217
    Schlagwort(e): EGF receptor ; HER2 ; HER3 ; HER4 ; heterodimerization ; tyrosine phosphorylation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The EGF receptor (EGFR) and HER2 are members of a growth factor receptor family. Overexpression of either protein in advanced breast cancer correlates with poor prognosis. EGF stimulates growth by binding to EGFR, activating the receptor's intracellular tyrosine kinase. The initial consequence is phosphorylation of specific tyrosine-containing sequences in the receptor's carboxyl terminus. These phosphotyrosines serve as high affinity recognition sites for proteins that, in turn, transmit the growth signal inside the cell. Mechanistic studies suggest that EGF binds to a single EGFR, triggering dimerization with another like receptor molecule. This dimerization is thought to initiate the tyrosine kinase activation. The EGF receptor family was recently expanded with the sequencing of HER3 and HER4. Each of the four family members was postulated to regulate a unique growth or differentiation signaling repertoire when activated by a receptor-specific ligand. However, new data from numerous laboratories suggest that EGFR family members may play a complex and ultimately more flexible role in signaling by forming heterodimers between family members, e.g. EGFR:HER2 or HER4:HER2. These heterodimers may form even when only one member of the pair binds its ligand. This review summarizes current work on heterodimerization and attempts to predict the consequences for downstream signaling. In brief, when compared to ligand-dependent receptor homodimers comprised of two proteins with the same internalization sequence and phosphorylated tyrosine residues, heterodimers are likely to: i) expand substrate selection and downstream signaling pathway activation; ii) promote interaction between sets of substrates in the mixed receptor complexes that would not ordinarily be physically juxtaposed; iii) alter the duration of receptor signaling by changing rates of receptor internalization, ligand loss, kinase inactivation, recycling, etc.; and iv) alter rates of receptor and substrate dephosphorylation. In addition to understanding interactions of heterodimers with the internalization machinery, identification of receptor-specific substrates and binding proteins for each EGFR family member will be necessary to explicate the role of heterodimers in growth and differentiation.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 41 (1993), S. 451-458 
    ISSN: 0006-3592
    Schlagwort(e): immobilized glucose isomerase ; substrate protection ; reactor analysis ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The effect of substrate protection on enzyme deactivation was studied in a differential bed and a packed bed reactor using a commercial immobilized glucose isomerase (Swetase, Nagase Co.). Experimental data obtained from differential bed reactor were analyzed based on Briggs-Haldane kinetics in which enzyme deactivation accompanying the protection of substrate was considered. The deactivation constant of the enzyme-substrate complex was found to be about half of that of the free enzyme. The mathematical analysis describing the performance of a packed bed reactor under the considerations of the effects of substrate protection, diffusion resistance, and enzyme deactivation was studied. The system equations for the packed bed reactor were solved using an orthogonal collocation method. The presence of substrate protection and the diffusion effect within the enzyme particles resulted in an axial variation of effectiveness factor, ηD, along the length of the packed bed. The axial distribution profile of ηD was found to be dependent on the operation temperature, Based on the effect of substrate protection, a better substrate feed policy could be theoretically found for promoting productivity in long-term operation. © 1993 John Wiley & Sons, Inc.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
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