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  • Florida  (3)
  • Behavioral sensitization  (2)
  • 1
    ISSN: 1432-2072
    Keywords: Cocaine ; Nimodipine ; Haloperidol ; L-type Ca2+ channels ; Behavioral sensitization ; Classical conditioning ; Conditioned locomotion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The classical conditioning of the behavioural effects of cocaine has been shown to contribute to behavioural sensitization. In the present experiments, it was demonstrated that the effects of cocaine in rats can be conditioned to contextual stimuli. Furthermore, sensitization to cocaine's locomotor effects were demonstrated, and shown to be context specific. Nimodipine (10 mg/kg, SC), an L-type dihydropyridine Ca2+ channel antagonist, appeared to completely block the establishment of conditioning of cocaine's effects, but only partially blocked sensitization to cocaine. Haloperidol (0.05 mg/kg, IP), a relatively specific D2 dopamine receptor antagonist, attenuated behavioral sensitization but had no influence on the establishment of the conditioned component of cocaine. These results indicate that the sensitization to, and the development of classical conditioning of, cocaine's behavioural effects can be pharmacologically dissociated, but that a non-associative process involved in sensitization is normally overridden by conditioning factors.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Cocaine ; Nimodipine ; Haloperidol ; L-type Ca2+ channels ; Dopamine receptors ; Behavioral sensitization ; Conditioned locomotion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The development of classical conditioning of cocaine's locomotor effects can be dissociated from the development of sensitization to cocaine by co-administration of haloperidol, a dopamine D2-like receptor antagonist, and nimodipine, an L-type calcium channel antagonist. The effects of these agents on theexpression of conditioning and sensitization are described in the present report. Rats were given injections of vehicle or cocaine (10 mg/kg, IP) for 10 days before placement in a specific context in which locomotor activity was recorded. Neither haloperidol (0.05 mg/kg, IP) nor nimodipine (10 mg/kg, SC) influenced the expression of classical conditioning of cocaine's locomotor effects to the situational context on a subsequent cocaine-free test. Combined treatment of rats with both drugs did block classical conditioning with cocaine. Nimodipine, but not haloperidol, blocked the expression of behavioural sensitization to cocaine after a cocaine challenge. It is concluded that the expression of cocaine-induced classical conditioning can be pharmacologically dissociated from the expression of behavioural sensitization to cocaine. Furthermore, the effects of nimodipine and haloperidol on the expression of conditioning and sensitization are different from their effects on the development of these phenomena.
    Type of Medium: Electronic Resource
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  • 3
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    In:  http://aquaticcommons.org/id/eprint/5593 | 3 | 2011-09-29 14:46:55 | 5593 | Florida Cooperative Fish and Wildlife Research Unit
    Publication Date: 2021-07-11
    Description: Hatchling American Alligators (Alligator mississippiensis) produced from artificially incubatedwild eggs were returned to their natal areas (repatriated). We compared artificially incubated andrepatriated hatchlings released within and outside the maternal alligator’s home range with naturallyincubated hatchlings captured and released within the maternal alligator’s home range on Lake Apopka,Lake Griffin, and Orange Lake in Florida. We used probability of recapture and total length at approximatelynine months after hatching as indices of survival and growth rates. Artificially incubated hatchlings releasedoutside of the maternal alligator’s home range had lower recapture probabilities than either naturallyincubated hatchlings or artificially incubated hatchlings released near the original nest site. Recaptureprobabilities of other treatments did not differ significantly. Artificially incubated hatchlings wereapproximately 6% shorter than naturally incubated hatchlings at approximately nine months after hatching.We concluded that repatriation of hatchlings probably would not have long-term effects on populationsbecause of the resiliency of alligator populations to alterations of early age-class survival and growth rates ofthe magnitude that we observed. Repatriation of hatchlings may be an economical alternative to repatriationof older juveniles for population restoration. However, the location of release may affect subsequent survivaland growth.
    Description: This document was submitted by the Florida Cooperative Fish and Wildlife Research Unit
    Keywords: Biology ; Ecology ; Management ; Lake Apopka ; Lake Griffin ; Orange Lake ; Florida ; Alligator mississippiensis ; American alligator
    Repository Name: AquaDocs
    Type: article
    Format: application/pdf
    Format: application/pdf
    Format: 415-423
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  • 4
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    In:  http://aquaticcommons.org/id/eprint/5061 | 3 | 2011-09-29 15:29:37 | 5061 | Florida Cooperative Fish and Wildlife Research Unit
    Publication Date: 2021-07-08
    Description: Proportions of American alligator (Alligator mississippiensis) nests sightedduring aerial survey in Florida were estimated based upon multiple surveys by differentobservers. We compared sighting proportions across habitats, nesting seasons, and observerexperience levels. The mean sighting proportion across all habitats and years was0.736 (SE=0.024). Survey counts corrected by the mean sighting proportion reliablypredicted total nest counts (R2=0.933). Sighting proportions did not differ by habitattype (P=0.668) or year P=0.328). Experienced observers detected a greater proportionof nests (P〈O.OOOl) than did either less experienced or inexperienced observers. Reliableestimates of nest abundance can be derived from aerial counts of alligator nestswhen corrected by the appropriate sighting proportion.
    Keywords: Biology ; Management ; American alligator ; Alligator mississippiensis ; aerial surveys ; nesting ; Florida
    Repository Name: AquaDocs
    Type: article
    Format: application/pdf
    Format: application/pdf
    Format: 314-321
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  • 5
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    In:  http://aquaticcommons.org/id/eprint/5060 | 3 | 2011-09-29 15:29:32 | 5060 | Florida Cooperative Fish and Wildlife Research Unit
    Publication Date: 2021-07-08
    Description: Alligator mississippiensis (American Alligators) demonstrated low hatchratesuccess and increased adult mortality on Lake Griffin, FL, between 1998 and2003. Dying Lake Griffin alligators with symptoms of poor motor coordination werereported to show specific neurological impairment and brain lesions. Similar lesionswere documented in salmonines that consumed clupeids with high thiaminase levels.Therefore, we investigated the diet of Lake Griffin alligators and compared it withalligator diets from two lakes that exhibited relatively low levels of unexplainedalligator mortality to see if consumption of Dorosoma cepedianum (gizzard shad)could be correlated with patterns of mortality. Shad in both lakes Griffin and Apopkahad high levels of thiaminase and Lake Apopka alligators were consuming greateramounts of shad relative to Lake Griffin without showing mortality rates similar toLake Griffin alligators. Therefore, a relationship between shad consumption aloneand alligator mortality is not supported.
    Keywords: Biology ; Environment ; Health ; Alligator mississippiensis ; American alligators ; Lake Griffin ; Florida ; nutrition ; Dorosoma cepedianum ; Gizzard shad ; mortality
    Repository Name: AquaDocs
    Type: article
    Format: application/pdf
    Format: application/pdf
    Format: 97-110
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