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  • 1
    ISSN: 1434-0879
    Keywords: Aromatization ; BPH ; Prostate cancer ; Prostatic secretions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Human prostatic tissue and expressed prostatic secretions (EPS) efrom patients with benign prostatic hyperplasia (BPH) and prostate cancer were incubated with (1 β 3H) androstenedione. The extent of aromatization was determined by measuring the transfer of 3H from the 1 β position into water. The amount of 3H2O recovered corresponds to the estrogens formed. Tissue from 5 patients with BPH yielded 2.13 (±1.05) pmol/mg protein/h while the EPS from the same patients yielded 727 fmol/mg protein/h. In patients with prostate cancer the mean formation of estrogens was 388 fmol/mg protein/h (±75). 4-hydroxyandrostenedione, an aromatase inhibitor, successfully inhibited aromatization in BPH and prostate cancer 53–98%.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 12 (1988), S. 75-78 
    ISSN: 1432-5195
    Keywords: Ultrasound ; Congenital disorders ; Hip
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'ultrasonographic a été utilisée parallélement à l'examen clinique pour le diagnostic et la surveillance du traitement de 48 nouveau-nés et nourrissons atteints de malformation congénitale de la hanche. L'ultrasonographie peut montrer la tête fémorale et ses rapports avec le cotyle avant que sa portion calcifiée ne soit radioopapque et prévient ainsi le danger d'irradiation. Cette technique peut également être réalisé chez des nourrissons porteurs d'attelles d'abduction ou de plâtres fenêtrés et vérifie la reposition d'une tête fémorale subluxée. L'ultrasonographie nous paraît être devenue un outil diagnostique et de surveillance de premiére importance chez les nourrissons atteints de malformation congénitale de la hanche, avant et aprés traitement.
    Notes: Summary Ultrasound was used, together with clinical examination, to help in the diagnosis and to evaluate the treatment of 48 babies with congenital disorders of the hip. The femoral head, and its relation to the acetabulum, can be demonstrated before it becomes visible on radiographs. Ionising radiation is avoided. Ultrasound scanning can be used to visualise the repositioning of the femoral head. It is also possible to examine babies on an abduction frame.
    Type of Medium: Electronic Resource
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