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  • 1
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Antisense nucleic acids. ; Antisense DNA. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (683 pages)
    Edition: 1st ed.
    ISBN: 9780080496719
    Series Statement: Issn Series
    Language: English
    Note: Front Cover -- Antisense Technology -- Copyright Page -- Table of Contents -- Contributors to Volume 314 -- Preface -- Volumes in Series -- Section I: Antisense Receptor Targets -- Chapter 1. In Vivo Modulation of G Proteins and Opioid Receptor Function by Antisense Oligodeoxynucleotides -- Chapter 2. Targeting Brain GABAA Receptors with Antisense Oligonucleotides: Implications for Epilepsy -- Chapter 3. Delivery of Antisense DNA by Vectors for Prolonged Effects in Vitro and in Vivo -- Chapter 4. Antisense Mapping: Assessing Functional Significance of Genes and Splice Variants -- Chapter 5. In Vitro and in Vivo Effects of Antisense on alpha2-Adrenoceptor Expression -- Chapter 6. Design and Efficacy of a Serotonin-2A Receptor Antisense Oligodeoxynucleotide -- Chapter 7. Reduction of Neurotransmitter Receptor and G-Protein Expression in Vivo and in Vitro by Antisense Oligodeoxynucleotide Treatment -- Chapter 8. Use of Expression of Antisense mRNA for Convertases 1 and 2 in Prohormone Processing -- Section II: Antisense Neuroscience Targets -- Chapter 9. Strategies for the Design and Delivery of Antisense Oligonucleotides in Central Nervous System -- Chapter 10. Use of Antisense Expression Plasmids to Attenuate G-Protein Expression in Primary Neurons -- Chapter 11. Gene Functional Analysis in Nervous System -- Chapter 12. RNA Mapping: Selection of Potent Oligonucleotide Sequences for Antisense Experiments -- Chapter 13. Effects of Centrally Administered Antisense Oligodeoxynucleotides on Feeding Behavior and Hormone Secretion -- Chapter 14. Blockade of Neuropathic Pain by Antisense Targeting of Tetrodotoxin-Resistant Sodium Channels in Sensory Neurons -- Chapter 15. Antisense Approach for Study of Cell Adhesion Molecules in Central Nervous System. , Chapter 16. Sequence Design and Practical Implementation of Antisense Oligonucleotides in Neuroendocrinology -- Chapter 17. Localization of Oligonucleotides in Brain by in Situ Hybridization -- Chapter 18. Use of Antisense Oligonucleotides in Human Neuronal and Astrocytic Cultures -- Cnapter 19. Pharmacokinetic Properties of Oligonucleotides in Brain -- Chapter 20. Antisense Oligonucleotides: Preparation and in Vivo Application to Rat Brain -- Chapter 21. Application of Antisense Techniques to Characterize Neuronal Ion Channels in Vitro -- Section III: Antisense in Nonneuronal Tissues -- Chapter 22. Antisense Inhibition of Sodium-Calcium Exchanger -- Chapter 23. Targeted Delivery of Antisense Oligonucleotides to Parenchymal Liver Cell in Vivo -- Chapter 24. Antisense Methods for Discrimination of Phenotypic Properties of Closely Related Gene Products: Jun Kinase Family -- Chapter 25. Evaluation of Biological Role of c-Jun N-Terminal Kinase Using an Antisense Approach -- Chapter 26. Role of Antisense in Kidney Cells -- Chapter 27. Use of Antisense Techniques in Rat Renal Medulla -- Chapter 28. Antisense Approaches to in Vitro Organ Culture -- Chapter 29. In Vivo and in Vitro Antiproliferative Effects of Antisense Interleukin 10 Oligonucleotides -- Chapter 30. Inhibition of c-ABL Expression in Hematopoietic Progenitor Cells Using Antisense Oligodeoxynucleotides -- Chapter 31. Cellular Pharmacology of Antisense Oligodeoxynucleotides -- Chapter 32. Application of Antisense Oligodeoxynucleotides for Suppression of Na+/Ca2+ Exchange -- Chapter 33. Optimizing Efficacy of Antisense Oligodeoxynucleotides Targeting Inhibitors of Apoptosis -- Section IV: Antisense in Therapy -- Chapter 34. In Vitro and in Vivo Modulation of Transforming Growth Factor beta1 Gene Expression by Antisense Oligomer. , Chapter 35. Analysis of Cancer Gene Functions through Gene Inhibition with Antisense Oligonucleotides -- Chapter 36. Dosimetry and Optimization of in Vivo Targeting with Radiolabeled Antisense Oligodeoxynucleotides: Oligonucleotide Radiotherapy -- Chapter 37. Antisense Oligonucleotide Therapy of Hepadnavirus Infection -- Chapter 38. Preclinical Antisense DNA Therapy of Cancer in Mice -- Chapter 39. Retrovirally Mediated Delivery of Angiotensin II Type 1 Receptor Antisense in Vitro and in Vivo -- Author Index -- Subject Index.
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