ISSN:
1750-3841
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Studies were made on the components of lysosomes. Analyses were based upon the distribution of constituents between the insoluble fraction containing the membrane and bound proteins and tbe soluble fraction containing released enzymes. Results were compared with those obtained for mitochondria and microsomes. The composition of the lysosomal membrane was characteristic of a unit phospholipid-protein membrane. The sialic acid content of lysosomes was not much greater than that found in other subcellular fractions, suggesting that sialopolymers are not involved in a special role in lysosomes. The released enzyme fraction, which contained about myc of the total protein, also contained free flavins and free amino acids in amounts very much larger than those observed for mitochondria. Fe, Zn, Cu, Mn, and MO were the principal metals concentrated in lysosomes. The relationship between the chemical composition, structure, and function of lysosomes is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2621.1965.tb01792.x
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