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  • 1
    Electronic Resource
    Electronic Resource
    Molecular epidemiology of human rotavirus infections (1985)
    Springer
    European journal of epidemiology 1 (1985), S. 19-32 
    Details
    ISSN: 1573-7284
    Keywords: Molecular epidemiology ; Rotavirus ; Electrophoresis ; RNA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Recognition of rotaviruses as a major aetiological agent of acute gastroenteritis in infants and young children has prompted the investigation of their epidemiology by molecular techniques. Genome analysis by electrophoretic separation of the RNA segments has been widely used to distinguish virus isolates and to monitor patterns of virus transmission. Examination of virus isolates from different epidemics has clearly demonstrated the existance of extensive genomic variation in viruses circulating in large communities; with the co-circulation of a number of viruses of differing electrophoretype. Preliminary studies using the more advanced techniques of oligonucleotide mapping and hybridization analysis have suggested that variation among the viruses may occur by processes involving both ≪ drift ≫ and ≪ shift ≫. Because of their ease and specificity the new hybridization analysis techniques should greatly facilitate both the rapid diagnosis of rotavirus infections, and the solution of many epidemiological and evolutionary questions. Continued and expanded use of molecular techniques for the study of the epidemiology of rotavirus infections will be required to manage future outbreaks and to effect long term control measures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00162308
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    An Intercomparison of NO2 and OClO Measurements at Arrival Heights, Antarctica during Austral Spring 1996 (1999)
    Springer
    Journal of atmospheric chemistry 33 (1999), S. 283-298 
    Details
    ISSN: 1573-0662
    Keywords: stratospheric trace gases ; Antarctica ; NO2 ; OClO
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Geosciences
    Notes: Abstract For several years NO2 and OClO, two species important to understanding ozone destruction in the Antarctic stratosphere, have been measured at Arrival Heights, Antarctica by two groups: New Zealand's National Institute of Water and Atmospheric Research (NIWA) and the NOAA Aeronomy Laboratory in Boulder, Colorado. Using data independently collected by these two groups during the Austral spring of 1996, it is shown that the two data sets are in extremely close agreement. Besides offering validation of the instrumentation and analysis techniques of both groups, this result provides confidence in the more complete history of these species gained by combining the two data sets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006185027584
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    Paper (German National Licenses)
    Fulltext
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