ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The electron impact (EI) and field ionization (FI) mass spectra of some representative underivatized cardenolides have been studied together for the first time, with the objective of assessing the structural and in particular the sequence information afforded by this promising analytical method. Two series of cardenolides have been examined, each consisting of a mono-, di- and trisaccharide glycoside. The first was based on the aglycone digitoxigenin and comprised neriifolin, thevebioside and cerberoside; the second was based on the genin strophantidin and included cymarin, K-strophantin-β and K-strophantoside. Other cardiac glycosides investigated and discussed include digitoxin and helveticoside. Important and structurally diagnostic fragmentations have been uncovered, especially in FI mode. In addition, the EI and FI spectra of individual components of the cardenolides have been recorded, e.g. the genins digitoxigenin and strophantidin, and the mono-saccharides L-thevetose, D-cymarose and D-glucose.
Additional Material:
13 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210050509
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