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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 39 (1977), S. 113-120 
    ISSN: 1432-1246
    Keywords: Lead ; Iron ; Sex ; Contraceptives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A study has been performed in 148 non occupationally exposed subjects (19–21 yrs) divided into three groups: males, females without and females using oral contraceptives. PbB-levels ranged from 46 to 238 ppb. Freeerythrocyte-porphyrins (FEP), serum iron (Fe-S), Hb, Ht, total iron-bindingcapacity and unsaturated-iron-binding-capacity were measured. A negative correlation was found between PbB and Fe-S in males only. In females FEP was higher than in males at same PbB-levels. Females using oral contraceptives had higher Fe-S-levels and total-iron-binding-capacity than females not taking these; no difference was found between individual preparations. Two hypotheses are suggested to explain the negative relationship between lead in blood and serum iron in males. In a study of 51 other male subjects, 19-21 yrs, again a negative trend for Fe-S with increasing PbB was observed; the pooled data showed a negative relation; there was no difference in morning and afternoon Fe-S levels.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 49 (1982), S. 265-273 
    ISSN: 1432-1246
    Keywords: Cadmium ; Biological monitoring ; Age ; Smoking habits
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Biological assessment of occupational exposure to cadmium in five different factories with low-level second degree usage of Cd-compounds has been carried out. In 124 exposed and control male workers the following measurements were performed: cadmium in blood (CdB) and urine (CdU), B2-microglobulin (B2M), creatinin in urine (Great), hemoglobin (Hb) and hematocrit (Ht). Analysis of 34 pairs of workers matched according to age, smoking habits, ethnic origin and factory, established a significant difference only in CdU, the geometric means being 0.67 μg/g Creat in the exposed group and 0.48 μg/g Creat in the control group. Significant correlation was found between CdU x age and CdB x smoking habits. Multiple regression analysis showed that for each year increase in age CdU increased 3%, for each percent increase of CdB CdU increased 0.28%; for each cigarette smoked per day CdB increased 1.6%. It is concluded that in this type of work the low external cadmium exposure does not express itself in different CdB-levels, but only in different CdU-levels, indicating an increased body burden due to long term low level occupational cadmium exposure. In biological assessment of exposure to Cd, it is essential to take age and smoking habits fully into account.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 42 (1979), S. 231-239 
    ISSN: 1432-1246
    Keywords: Lead ; Cadmium ; Zinc ; Manganese ; Porphyrin ; Children ; Smelter ; Biological quality guide for lead
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 108 two-and three-year-old children the concentration of lead, cadmium, manganese, and zinc in blood, of free erythrocyte porphyrin in erythrocytes, and of haemoglobin and haematocrit were measured. The relation with distance of residence to a secondary smelter and with socio-economic class was studied. The ranges were for PbB 45–383 ppb, CdB 0.2–3.5 ppb, ZnB 2.0–9.7 ppm, MnB 2.7–14.1 ppb, FEP 10.5–138.9 μg/100 ml rbc. PbB was influenced independently by the distance to the source of emission and by the socioeconomic class. FEP increased with PbB; Hb and Ht were not affected. The results suggest that the Biological Quality Guide for blood lead as adopted in the European Community may have to be lowered for young children.
    Type of Medium: Electronic Resource
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