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  • 1
    Electronic Resource
    Electronic Resource
    Authenticity assessment of 2- and 3-methylbutanol using enantioselective and/or 13C/12C isotope ratio analysis (1999)
    Springer
    European food research and technology 209 (1999), S. 12-15 
    Details
    ISSN: 1438-2385
    Keywords: Key words 2-Methylbutanol ; 3-Methylbutanol ; Carbon-13/carbon-12 isotope ratio analysis ; Gas chromatography-isotopic ratio mass spectrometry ; Authenticity assessment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract  Enantioselective gas chromatography and/or 13C/12C isotope ratio analysis are suitable tools for the authenticity assessment of the fusel alcohols, 2- and 3-methylbutanol (1 and 2, respectively). The chiral compound, 1 is biosynthesised almost completely as the (S)-enantiomer, regardless of which carbohydrate source is used for fermentation. The type of CO2 fixation and some plant-specific influences were of prime importance to the 13C/12C isotope ratios of the starting materials in alcoholic fermentation, and the δ13C values of 1 and 2 differed significantly. In general, the δ13C values of 2 were about 4–5ö lower than those of 1 produced via the same fermentation process. 13C/12C isotope ratio analysis results can be used to determine between fusel alcohols produced from different sources, and provides a new and valuable method of authenticity assessment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002170050448
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of DAS on respiration and pulmonary vascular resistance (1971)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 271 (1971), S. 289-293 
    Details
    ISSN: 1432-1912
    Keywords: “Depressor Active Substance” (DAS) ; Vagotonus ; Pulmonary Vascular Resistance ; Bronchoconstriction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In stored blood as well as in various organs, a substance appears which causes a marked drop of systemic blood pressure after intravenous injection. The active principle was called “depressor active substance” (DAS). In order to study the circulatory effects of DAS the systemic and the pulmonary vascular resistance (SVR and PVR) and the ventilation volume were measured. DAS stopped respiratory movements by exciting afferent vagus fibres and led to an abnormal cardiac activity and to bronchoconstriction by stimulation of the vagotonus. Furthermore, DAS showed a direct bronchoconstrictor effect. The application of DAS caused a strong increase of PVR. This effect was strong enough to produce an abrupt drop of the systemic blood pressure because of a reduced diastolic filling of the left ventricle. Higher quantities of DAS led to an acute insufficiency of the right ventricle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00997222
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    Paper (German National Licenses)
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