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  • BZLF1  (2)
  • 187-1154A; 187-1155A; 187-1155B; 187-1156A; 187-1158B; 187-1158C; 187-1160B; 187-1161A; 187-1162A; 187-1164A; Aluminium oxide; Aluminium oxide, standard deviation; Calcium oxide; Calcium oxide, standard deviation; Calculated; Chromium(III) oxide; Chromium(III) oxide, standard deviation; DRILL; Drilling/drill rig; DSDP/ODP/IODP sample designation; Electron microprobe JEOL JXA-8900; Elements, total; Elements, total, standard deviation; Elevation of event; Enstatite; Enstatite, standard deviation; Event label; Ferrosilite; Ferrosilite, standard deviation; Grains, counted/analyzed; Indian Ocean; Iron oxide, FeO; Iron oxide, FeO, standard deviation; Joides Resolution; Latitude of event; Leg187; Longitude of event; Magnesium number; Magnesium number, standard deviation; Magnesium oxide; Magnesium oxide, standard deviation; Manganese oxide; Manganese oxide, standard deviation; Nickel oxide; Nickel oxide, standard deviation; Ocean Drilling Program; ODP; Potassium oxide; Potassium oxide, standard deviation; Sample code/label; Sample comment; Silicon dioxide; Silicon dioxide, standard deviation; Sodium oxide; Sodium oxide, standard deviation; Titanium dioxide; Titanium dioxide, standard deviation; Vanadium oxide; Vanadium oxide, standard deviation; Wollastonite; Wollastonite, standard deviation  (1)
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  • 1
    facet.materialart.
    Unknown
    (Supplement Table 2) Chemical compositions of pyroxene grains in lavas collected from ODP Leg 187 sites (2004)
    PANGAEA
    Details
    Publication Date: 2024-01-09
    Keywords: 187-1154A; 187-1155A; 187-1155B; 187-1156A; 187-1158B; 187-1158C; 187-1160B; 187-1161A; 187-1162A; 187-1164A; Aluminium oxide; Aluminium oxide, standard deviation; Calcium oxide; Calcium oxide, standard deviation; Calculated; Chromium(III) oxide; Chromium(III) oxide, standard deviation; DRILL; Drilling/drill rig; DSDP/ODP/IODP sample designation; Electron microprobe JEOL JXA-8900; Elements, total; Elements, total, standard deviation; Elevation of event; Enstatite; Enstatite, standard deviation; Event label; Ferrosilite; Ferrosilite, standard deviation; Grains, counted/analyzed; Indian Ocean; Iron oxide, FeO; Iron oxide, FeO, standard deviation; Joides Resolution; Latitude of event; Leg187; Longitude of event; Magnesium number; Magnesium number, standard deviation; Magnesium oxide; Magnesium oxide, standard deviation; Manganese oxide; Manganese oxide, standard deviation; Nickel oxide; Nickel oxide, standard deviation; Ocean Drilling Program; ODP; Potassium oxide; Potassium oxide, standard deviation; Sample code/label; Sample comment; Silicon dioxide; Silicon dioxide, standard deviation; Sodium oxide; Sodium oxide, standard deviation; Titanium dioxide; Titanium dioxide, standard deviation; Vanadium oxide; Vanadium oxide, standard deviation; Wollastonite; Wollastonite, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 928 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 2
    Electronic Resource
    Electronic Resource
    Elevation of antibody against Epstein-Barr virus genes BRLF1 and BZLF1 in nasopharyngeal carcinoma (2000)
    Springer
    Journal of cancer research and clinical oncology 126 (2000), S. 69-73 
    Details
    ISSN: 1432-1335
    Keywords: Key words Nasopharyngeal carcinoma ; Epstein-Barr virus ; BZLF1 ; BRLF1 ; Serology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: Epstein-Barr virus immediate early genes BZLF1 and BRLF1 encode the Z and R proteins respectively. Elevation of the anti-Z immunoglobulin (Ig) antibody titer is a common feature of nasopharyngeal carcinoma (NPC) in areas where the disease endemic, whereas R levels have not been examined. This study was performed to analyze antibody titers against Z and R in Japan. Methods: Sera from 14 patients with newly diagnosed NPC, 7 with NPC in complete remission, 15 with head and neck squamous cell carcinoma (HNSCC), and 31 controls were evaluated by enzyme-linked immunosorbent assay (ELISA) and immunoblotting. Results: Both anti-Z and anti-R Ig were significantly increased in sera from patients with NPC compared with those in remission, those with HNSCC, and controls (Z, P = 0.0016, = 0.0344, = 0.0002; R, P = 0.0015, = 0.0004, 〈0.0001 respectively). By immunoblot analysis, anti-Z and anti-R Ig were detected in 9 of 9 cases of NPC, 1 of 3 cases NPC in remission, and 2 of 13 cases of HNSCC. Anti-Z and anti-R antibody titers were nine times higher in NPC than in other groups. None of 15 control cases showed positive reactivity against either Z or R. Conclusion: Coupled evaluation of anti-Z and anti-R Ig by ELISA might be a useful system for screening NPC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004320050011
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Matrix metalloproteinase 9 is induced by the Epstein–Barr virus BZLF1 transactivator (1999)
    Springer
    Clinical & experimental metastasis 17 (1999), S. 431-436 
    Details
    ISSN: 1573-7276
    Keywords: EBV ; BZLF1 ; metastasis ; MMP ; nasopharyngeal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Type IV collagenases, matrix metalloproteinase (MMP) 2 and MMP9 are implicated in tumor invasion and metastasis. In patients with nasopharyngeal carcinoma (NPC), poor prognosis due to development of local and distant metastasis has been reported to be predicted by antibody titers against the Z protein which is an AP-1 family transcription factor encoded by the EBV BZLF1 immediate-early gene. Here we report that in patients with NPC, expression of Z in tumor cells correlates with advanced cervical lymph node metastasis which may suggest that Z affects tumor invasion and metastasis. We therefore tested if Z would induce expression of type IV collagenases. Transfection of Z expression plasmid into the C33A epithelial cell line increased expression of MMP9, but MMP2 expression was unaltered. Mutational analysis of the Z protein revealed that, in addition to all three functional domains of Z (dimerization domain, DNA binding domain, and activation domain), the carboxyl terminal 17 amino acids which stabilize the Z protein were necessary for induction of MMP9 expression. Analysis of the MMP9 promoter demonstrated that only AP-1 site close to the transcriptional start-site was essential for transactivation by Z. Previously we reported that Epstein–Barr virus latent membrane protein 1 (LMP1) stimulates MMP9 expression (Yoshizaki et al. Proc. Natl. Acad. Sci. 1998; 95: 3621–6). Thus, Z together with LMP1 may contribute to invasion and metastasis of NPC by inducing expression of MMP9.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006699003525
    Location Call Number Limitation Availability
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    Paper (German National Licenses)
    Fulltext
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