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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    European journal of epidemiology 15 (1999), S. 421-427 
    ISSN: 1573-7284
    Schlagwort(e): Biomarkers ; Cancer ; Elderly ; Epidemiology ; Mortality ; Risk factors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Cancer mortality was analysed in 3282 elderly subjects aged ≥ 65 years from 2 cohorts of general population having different life-style patterns. They took part in the CASTEL (CArdiovascular STudy in the ELderly), a 12-year lasting prospective Italian study. The aim of the present analysis was to identify the items able to influence cancer mortality. A biochemical profile and a questionnaire on lifestyle were collected. Continuous items were averaged and compared with analysis of variance, frequencies with the Pearson's ϰ2 test. Mortality was recorded yearly for 12 years from the Registrar's Office and causes of death double-checked by consulting medical case sheets and family doctors' files. The influence of items on mortality was evaluated with the Cox multivariate analysis. Relative risk (RR) of each item was adjusted for confounders. Age, gender, tobacco smoking, the presence of respiratory symptoms, low body mass index in males, serum alanine transaminase (ALT) and alkaline phosphatase (ALP), as well as the town of residence, were powerful predictors of cancer mortality. In the entire population, 12-year overall mortality was 49.4%, cardiovascular 22.8%, and neoplastic 11%; the latter was higher in males than in females (15.7% vs. 7.9%, p 〈 0.00001). In subjects with respiratory symptoms neoplastic mortality was 11.6% (RR: 1.47) vs. 9.7% in those without symptoms (p 〈 0.01). Subjects with very low cholesterol (≤ 178 mg/dl), those with high uric acid (≥ 8.7 mg/dl) and males with low body mass index (≤ 22.7 kg/m2) has an increased risk of cancer mortality. RR of cancer mortality increased with increasing ALT or ALP. It was ∼1 in those having ALT and ALP between 9 and 41.2U/I, 1.41 in those exceeding this latter level and 〈 1 in those below 9U/I. RR of ALP had a similar trend, the best protective cut-off value being 〈106 and the worst one 〉 177U/I. When both serum enzymes were simultaneously raised, RR of cancer mortality increased to 2.84.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Clinical rheumatology 15 (1996), S. 121-124 
    ISSN: 1434-9949
    Schlagwort(e): DISH ; Spine ; Epidemiology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Diffuse idiopathic skeletal hyperostosis (DISH) is a skeletal disease characterized by ligamentous ossification of the anterolateral side of the spine. The radiographs of the spine of 69 patients (22 males, 47 females, mean age 64.97±8.83 years) affected by DISH according to Resnick's criteria were selected. A lower rate of lumbar spine involvement (71%) and a different distribution between sexes were demonstrated, as compared to the data from the literature. Data on relationships among extent of hyperostosis, occupation and metabolic disorders suggest that an important role might be played by the exposure to microtrauma, while, in subjects affected by a metabolic disorder, this condition would represent a prevalent pathogenetic factor. These data underline some peculiarities in the clinical picture of DISH in the population from Campania, that could depend on genetic factors.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Publikationsdatum: 2012-02-03
    Beschreibung: Slow earthquakes and afterslips prove that the Earth does not have just two response time scales, i.e. that of tectonic loading and that of regular earthquakes. A swarm of slow earthquakes, with time constants of the order of hundreds of seconds, has been detected by a laser interferometer below the Gran Sasso massif (Italy). We analyse and model these observations to identify a very plausible source in a local fault, with no historic seismic behavior. While slow earthquakes occurring in subduction zones, and at the transition between locked and stably sliding segments of the San Andreas fault, are often associated with seismic events, in the case of the Apennines there is no correlation between local seismicity and slow earthquakes. Slow earthquakes, therefore, may also represent a specific failure behavior for a seismically locked fault, adding further complexity to the interpretation of geologic data for seismic hazard estimates.
    Beschreibung: Published
    Beschreibung: 2219
    Beschreibung: open
    Schlagwort(e): Earthquake dynamics and mechanics ; Seismic hazard assessment and prediction ; Seismicity and seismotectonics ; 04. Solid Earth::04.01. Earth Interior::04.01.05. Rheology ; 04. Solid Earth::04.06. Seismology::04.06.03. Earthquake source and dynamics
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article , article
    Format: 398488 bytes
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    facet.materialart.
    Unbekannt
    Seismological Society of America
    Publikationsdatum: 2017-04-04
    Beschreibung: The seismic activity associated with the catastrophic southern Italy earth- quake was monitored by 11 seismic stations operating before this event, within an epicentral distance of 200 km, and by 32 additional short-period seismom- eters installed soon after the main shock. The hypocenter of this event was located at 40°46'N and 15°18'E, at 16 km depth. The fault-plane solution reveals normal faulting, with tensile axis dipping 18 ° and oriented orthogonal to the axis of the Apennines chain. This mechanism is in good agreement with the stress pattern inferred from some previous earthquakes and the local seismotectonics. The hypocenter locations of more than 600 aftershocks, with local magnitudes greater than 2.4, show a pronounced alignment extending for about 70 km, oriented north 120 ° and scattered laterally less than 15 km. These events are mostly concentrated between 8 and 16 km depth. A cluster of aftershocks occurred close to the hypocenter of the main shock covering a region elongated 25 km which corresponds also to the highly damaged area. No significant spreading of the aftershock area with time is observed, but one of the events with higher magnitude (M, = 4.8, 14 February 1981) is displaced 20 km NW from the tip of the aftershock region. The time evolution of the number of aftershocks fits well Omorrs hyperbolic law with a decay coeffcient of 1.07 __. 0.06. The possibility of a future delayed multiple sequence of large events, as already observed in the past along the central and southern Apennines, is discussed. In particular, a relatively high seismic potential seems to exist along the northern boundary of the 1980 rupture segment.
    Beschreibung: Published
    Beschreibung: 187-200
    Beschreibung: 3.1. Fisica dei terremoti
    Beschreibung: JCR Journal
    Beschreibung: reserved
    Schlagwort(e): Irpinia Earthquake ; Aftershock sequences ; 04. Solid Earth::04.06. Seismology::04.06.03. Earthquake source and dynamics
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Publikationsdatum: 2019-11-04
    Beschreibung: Earthquake locations and fault-plane solutions are investigated in Sicily and the surrounding areas, by using local network data for the period 1988-1995, and a recently proposed 3D model of the local crustal structure. The results were used for local-to-regional scale stress inversion and strain tensor computations, after integration by a set of selected focal mechanisms taken from the literature. The area under study appears to be affected by heterogeneity of seismic deformation and the stress field. The contraction-to-extension transition from west to east on a regional scale can find a reasonable explanation in the framework of current geodynamic models, such as those assuming the activity of two main tectonic sources in the South Italy region, e.g., the Africa-Europe north-south slow convergence and the faster eastward roll-back of a westward-dipping Ionian subducting slab (Cinque al., 1993). The analysis of low-magnitude (2.5-4.0) earthquakes permitted us to perform an investigation of local-scale strain heterogeneities in this region and to evidence notable changes in the deformation style when processes at different scales are considered.
    Beschreibung: JCR Journal
    Beschreibung: open
    Schlagwort(e): stress ; strain ; lithosphere ; Sicily ; 04. Solid Earth::04.06. Seismology::04.06.03. Earthquake source and dynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.05. Stress ; 05. General::05.02. Data dissemination::05.02.02. Seismological data
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Format: 3980697 bytes
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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